We describe the use of a cryomold as a technique for tissue embedding in Mohs Micrographic Surgery. This technique regularly affords many advantages over other methods of tissue embedding, such as: 1) regularly and expeditiously yields complete margins for microscopic review; 2) facilitates flattening of large, thick, and irregularly shaped specimens; and 3) avoids crush artifact and tissue distortion that may be seen with forcible compression.