Chemotherapy for Primary and Recurrent Epithelial Ovarian Cancer

Abstract

Epithelial ovarian cancer is the second most common gynecological cancer. It causes more deaths despite advances in treatment over the last few decades. Following explorative surgery and after histological assessment, the tumor can be formally "staged" according to the size, extent and location of the cancer. Staging during surgery determines the appropriate treatment regimen and the long-term outcome (prognosis). Recommendations for treatment after surgery are dependent on the stage of the cancer. Chemotherapy is recommended after surgery for stage III or IV ovarian cancer; certain tumor factors determine its use in stage I or II disease.