Chi-Square Tests with One Degree of Freedom; Extensions of the Mantel- Haenszel Procedure

Mantel, Nathan

doi:10.2307/2282717

Cited by 1,096 publications

(283 citation statements)

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“…Spearman's rank test was used in correlation analysis. Adjustment for age was based on Mantel′s technique of pooling43 applied to Fisher′s non-parametric permutation test 44. No correction for multiple correlations was made.…”

Section: Methodsmentioning

confidence: 99%

CSF sulfatide distinguishes between normal pressure hydrocephalus and subcortical arteriosclerotic encephalopathy

Tullberg

Månsson²,

Fredman³

et al. 2000

Journal of Neurology, Neurosurgery &Amp; Psychiatry

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Objectives-To examine the CSF concentrations of molecules reflecting demyelination, neuronal and axonal degeneration, gliosis, monoaminergic neuronal function, and aminergic and peptidergic neurotransmission in a large series of patients with normal pressure hydrocephalus (NPH) or subcortical arteriosclerotic encephalopathy (SAE), to elucidate pathogenic, diagnostic, and prognostic features. Methods-CSF concentrations of glycosphingolipid (sulfatide), proteins (neurofilament triplet protein (NFL), glial fibrillary acidic protein (GFAP)), neuropeptides (vasoactive intestinal peptide (VIP), 4-aminobutyric acid (GABA)), and monoamines (homovanillic acid (HVA), 5-hydroxy-indoleacetic acid (5-HIAA), 4-hydroxy-3-methoxyphenylglycol (HMPG)) were analysed in 43 patients with NPH and 19 patients with SAE. The diagnoses of NPH and SAE were based on strict criteria and patients with NPH were subsequently operated on. Twelve clinical variables, psychometric tests measuring perceptual speed, accuracy, learning, and memory and a psychiatric evaluation were performed in all patients and before and after a shunt operation in patients with NPH. Results-The CSF sulfatide concentration was markedly increased in patients with SAE (mean 766, range 300-3800 nmol/l) compared with patients with NPH (mean 206, range 50-400 nmol/l) (p<0.001). 5-HIAA, GABA, and VIP in CSF were higher in patients with SAE than in patients with NPH. The patients with NPH with cerebrovascular aetiology had higher sulfatide concentrations and a poorer outcome after shunt surgery than patients with NPH with other aetiologies. Conclusions-The pathogenesis of the white matter changes in NPH and SAE is diVerent and ischaemic white matter changes can be a part of the NPH state. The markedly increased CSF sulfatide concentrations in patients with SAE indicate ongoing demyelination as an important pathophysiological feature of SAE. The CSF sulfatide concentration distinguished between patients with SAE and those with NPH with a sensitivity of 74% and a specificity of 94%, making it an important diagnostic marker.(J Neurol Neurosurg Psychiatry 2000;69:74-81)

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Section: Methodsmentioning

confidence: 99%

CSF sulfatide distinguishes between normal pressure hydrocephalus and subcortical arteriosclerotic encephalopathy

Tullberg

Månsson²,

Fredman³

et al. 2000

Journal of Neurology, Neurosurgery &Amp; Psychiatry

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“…For continuous variables the relevant t-tests for paired samples and for comparison of two independent means were used. A general test for trend was performed according to Mantel's method (20).…”

Section: Methodsmentioning

confidence: 99%

Menstruation Span – a Time‐Limited Risk Factor for Endometrial Carcinoma

Pettersson

Adami

Bergström

et al. 1986

Acta Obstet Gynecol Scand

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A case-control study was undertaken to investigate the influence of reproductive factors on the risk of developing endometrial carcinoma. The study comprised 254 women with newly diagnosed endometrial carcinoma, resident in a defined geographical area, and 254 age-matched population controls. Nulliparity and late menopause were positively associated with endometrial carcinoma. Each additional full-term pregnancy resulted in a decrease in the risk by 16%. The importance of parity and menopausal age decreased with increasing life span, and in women older than 69 years these two variables did not discriminate significantly between cases and controls. The calculated number of years of menstruation (the "menstruation span") was used as a combined measure of the impact of parity, age at menarche and age at menopause on the risk of developing endometrial carcinoma. The patients had a significantly longer mean menstruation span than the controls (33.6 versus 31.2 years; p less than 0.001) and a longer span than 39 years gave a 4.2 times higher risk than one shorter than 25 years. It is suggested that the total length of time for which a woman is exposed to unopposed estrogen is important and that the effect of this hormonal influence is time-limited.

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“…The results from the different groups were then pooled into a summarizing test concerning the partial correlation given the variables age and use/non-use of oral contraceptives [Ill. The P values were determined by means of Edgeworth's expansion [12]. Table I gives the individual premenstrual symptoms and their severity in decreasing order of frequency.…”

Section: Methodsmentioning

confidence: 99%

Premenstrual Complaints. I. Prevalence of Premenstrual Symptoms in a Swedish Urban Population

Andersch

Wendestam

Hahn

et al. 1986

Journal of Psychosomatic Obstetrics & Gynecology

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The prevalence of premenstrual discomfort was studied in a random sample of 1083 Swedish women. Data were collected by questionnaire and assessments were made by the use of a quantitative scoring system. Mental symptoms in combination with feelings of body-swelling were common, noted in two-thirds (70%) of the women. The prevalence of certain target symptoms of premenstrual discomfort was studied. The mental symptoms were irritability, sadness and anxiety, and the physical symptoms were swelling in 3 areas of the body. Premenstrual anxiety was the only mental symptom shown to increase with age (P < 0.01). The severity of the complaints was neither affected by parity nor by abnormal cycle lengths. Absence from work during the premenstruum was reported by a small number of women and was related to the severity of the premenstrual discomfort.

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Chi-Square Tests with One Degree of Freedom; Extensions of the Mantel- Haenszel Procedure

Cited by 1,096 publications

References 0 publications

CSF sulfatide distinguishes between normal pressure hydrocephalus and subcortical arteriosclerotic encephalopathy

CSF sulfatide distinguishes between normal pressure hydrocephalus and subcortical arteriosclerotic encephalopathy

Menstruation Span – a Time‐Limited Risk Factor for Endometrial Carcinoma

Premenstrual Complaints. I. Prevalence of Premenstrual Symptoms in a Swedish Urban Population

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