Chiasmal syndrome: Clinical characteristics in patients attending an ophthalmological center

Astorga-Carballo, Aline; Serna‐Ojeda, Juan Carlos; Camargo-Suarez, Mayra Fabiola

doi:10.1016/j.sjopt.2017.08.004

Cited by 14 publications

(17 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Dyschromatopsia as tested using Ishihara color plates was seen in all cases (100%), involving 22 eyes. This is higher compared to a study by Astorga 9 , affecting only 62.5% of their cases, which probably is due to the fact that most of the patients presented in the late course of the disease.…”

Section: Chiasmal Syndrome Can Have a Variety Of Clinical Manifestations With Low Vision As The Initial Presentationcontrasting

confidence: 69%

See 1 more Smart Citation

Case Series on Chiasmal Lesions with Ocular Manifestations seen at the Eye Center of a Tertiary Government Hospital in Philippines

Amir

Ang

2020

JOS

View full text Add to dashboard Cite

Objective To identify common ocular and non-ocular signs and symptoms of patients with chiasmal lesions presenting to ophthalmologists. Methods This is a three year case series of patients who presented to Rizal Medical Center Ophthalmology OPD clinic, diagnosed as cases of chiasmal lesion with a complete neuro-ophthalmogical exam, ancillary test and neuroimaging. Data collected include patient profile, ocular and non ocular symptoms, duration of blurring of vision (BOV), best corrected visual acuity (BCVA), Color Vision, Optic nerve (ON) description, Visual field defects (VFD) and size & location of chiasmal lesion. Results A total of twelve patients were included with 1:1 M:F ratio and a median age of 39 years. Blurring of Vision was the presenting symptom in 10 cases, bulging of the eyes and headaches in the remaining cases. Associated symptoms include: non specific headache in all; diplopia in 3 (1 with and 2 without motility defects); and systemic symptoms related to hormonal imbalance in 2 cases. Best corrected vision ranged from 6/6 to no light perception (NLP). Color vision was affected in all cases. ON palor was seen in 6 (50%) and disc edema in 1 case. VFD include Junctional scotoma (58.33%), bitemporal hemianopia (33.3%) and generalised scotoma (8.3%). Neuroimaging revealed pituitary lesions in 10 cases, 1 craniopharyngioma and ON glioma with chiasmal extension. Conclusion Ocular and non ocular symptoms seen were comparable to other studies except that Junctional scotoma was the most common VFD identified in the included population of our case series. This highlights the importance of VF testing among patients complaining of unilateral visual loss to rule out a chiasmal lesion.

show abstract

Section: Chiasmal Syndrome Can Have a Variety Of Clinical Manifestations With Low Vision As The Initial Presentationcontrasting

confidence: 69%

“…The average Mean Deviation of 22 eyes is 21.79dB (8.3 to 38.45dB). Majority of eyes had MD of more than 10 dB as seen in table 5It is notable that in this case A retrospective study done by Astorga-Carballo et al9 with a larger population than ours (n = 104) observed a slight female predominance (1:1.47) and a median…”

supporting

confidence: 45%

Case Series on Chiasmal Lesions with Ocular Manifestations seen at the Eye Center of a Tertiary Government Hospital in Philippines

Amir

Ang

2020

JOS

View full text Add to dashboard Cite

show abstract

“…A pathological process in the chiasmal and sellar region results in the development of neuro-ophthalmic symptoms of chiasmal syndrome (CS) with decreased visual acuity, visual field defects and development of descending optic nerve atrophy. Other symptoms that may develop in CS include diplopia, impaired color perception, impaired stereoscopic vision, photophobia and a number of generalized symptoms like headache and hormonal abnormalities [5][6][7][8].…”

Section: Paul Bert a French Physiologistmentioning

confidence: 99%

“…Pupil responses are preserved or slightly reduced infrequently. Complete ophthalmoplegia is rare, and most commonly occurs in tumoral hemorrhage [2,6].…”

Section: Intrachiasmal Lesionsmentioning

confidence: 99%

Neuro-opthalmological aspect of chiasmal-and-sellar disorders

Vasyuta¹,

Pedachenko²

2018

Oftalmol Zh

View full text Add to dashboard Cite

This article reviews the causes, pathogenesis, and major manifestations of chiasmal syndrome. In addition, it reviews the methods for diagnosing the condition, and the course of the syndrome in patients with various chiasmal-and-sellar disorders such as pituitary adenoma, craniopharyngioma, tuberculum sellae meningioma, and skull base aneurysm. The principle neuro-ophthalmological symptoms include decreased visual acuity, bitemporal visual field defects, and development of descending optic nerve atrophy. Early detection of ophthalmological symptoms is of critical importance for timely neurosurgical treatment.

show abstract

“…Já, as fibras oriundas da retina nasal superior cruzam o quiasma óptico na sua porção mais superior e posterior e são geralmente afetadas por lesões que crescem superiormente a ele, como os craniofaringeomas, causando defeitos temporais inferiores de CV (29) . As fibras maculares geralmente se posicionam na região mais central e superior do quiasma óptico (30) .…”

Section: Anatomia Da Via óPtica Anteriorunclassified

Correlação entre a densidade capilar da retina peripapilar e macular medidas com a angiotomografia de coerência óptica e as medidas de espessura retiniana e campimetria visual em olhos com atrofia em banda do nervo óptico

Suzuki¹

View full text Add to dashboard Cite

Purpose: To compare the circumpapillary and superficial macular vessel density (cpVD and mVDsup) of eyes with temporal visual field (VF) defect and band atrophy (BA) of the optic nerve and normal controls using optical coherence tomography angiography (OCTA) and to verify the association of vessel density parameters with retinal neural loss assessed by conventional optical coherence tomography (OCT) and VF loss. Methods: Thirty-three eyes of 26 patients with BA and 42 eyes of 22 age-matched normal controls underwent OCT + OCTA scanning. cpVD and circumpapillary retinal nerve fiber layer (cpRNFL) thickness were expressed as average and sector measurements. mVDsup and macular ganglion cell complex (mGCC) thickness were calculated as averages and in quadrants and hemiretinas. VF loss was estimated using the 24-2 and the 10-2 protocols. Results: Compared with controls, BA eyes displayed smaller average cpVD and mVDsup values (p < 0.001 and AROC = 0.91 for both). Sectorial measurements were also reduced, especially the nasotemporal sector average cpVD (p < 0.001 and AROC = 0.96) and the nasal inferior retina mVDsup measurements (p < 0.001 and AROC = 0.93). cpVD and mVDsup correlated strongly (p<0,001) with corresponding cpRNFL and mGCC thickness measurements in affected regions (r range: 0.67-0.78 and 0.56-0.76, respectively). Similarly, cpVD and mVDsup parameters correlated significantly with corresponding VF loss (r range: 0.45-0.68). Conclusion: cpVD and mVDsup are significantly reduced in BA eyes compared with controls and are strongly correlated with retinal neural and VF loss. cpVD and mVDsup reduction on OCTA could serve as a surrogate for retinal neural loss in compressive optic neuropathy and might be useful in its management.

show abstract

Chiasmal syndrome: Clinical characteristics in patients attending an ophthalmological center

Cited by 14 publications

References 12 publications

Case Series on Chiasmal Lesions with Ocular Manifestations seen at the Eye Center of a Tertiary Government Hospital in Philippines

Case Series on Chiasmal Lesions with Ocular Manifestations seen at the Eye Center of a Tertiary Government Hospital in Philippines

Neuro-opthalmological aspect of chiasmal-and-sellar disorders

Correlação entre a densidade capilar da retina peripapilar e macular medidas com a angiotomografia de coerência óptica e as medidas de espessura retiniana e campimetria visual em olhos com atrofia em banda do nervo óptico

Contact Info

Product

Resources

About