Chikungunya

Amin, Robed; Rahman, Md. Mujibur; Islam, Quazi Tarikul

doi:10.3329/jom.v18i2.33687

Cited by 3 publications

(7 citation statements)

References 35 publications

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“…CF may also be accompanied by a rash, which can range in severity from a mild, localized rash to an extensive rash involving > 90% of the body surface [ 14 ]. Due to the multiplicity of CF symptoms, patients will mostly seek medical care for joint pain, swelling, and morning stiffness, which may persist for a prolonged period, often lasting even years [ 6 , 14 , 15 ]. A significant portion of patients also experience depression, sleeping disorders, and mood swings [ 15 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

“…Due to the multiplicity of CF symptoms, patients will mostly seek medical care for joint pain, swelling, and morning stiffness, which may persist for a prolonged period, often lasting even years [ 6 , 14 , 15 ]. A significant portion of patients also experience depression, sleeping disorders, and mood swings [ 15 , 16 ]. In addition, a minority of CF patients will report chronic joint complaints [ 15 ].…”

Section: Introductionmentioning

confidence: 99%

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Chikungunya outbreak in Bangladesh (2017): sociodemographic and clinical characteristics of patients from three hotspots

Amin

Hasan²,

Khan³

et al. 2022

Trop Med Health

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Background Chikungunya is a severely debilitating disease. Bangladesh witnessed one of the largest outbreaks in 2017. Here, we described the clinical profile of the chikungunya outbreak in Bangladesh and its heterogeneity across three hotspots. Methods This was a descriptive cross-sectional study of 432 individuals interviewed from the outpatient department of three study sites (Dhaka, Chittagong, and Sitakundu Upazilla of Bangladesh) after confirmation by the study physicians. Both laboratory-confirmed cases and probable cases were recruited between July and October 2017. Results Of all, 18% (79) were laboratory confirmed, and 353 82% (335) were probable cases. The male:female ratio was almost equal (1.09:1), and the predominant age group was 18–59 years. The mean age of the presentation was 36.07 ± 13.62 (SD) years. Fever and arthralgia were the most common presentations and were present in > 95% of cases. Other frequent symptoms were fatigue, myalgia, headache, nausea, and vomiting. Approximately half of the patients had arthritis and erythematous rash. Arthritis was predominant in Chittagong city, while maculopapular rash was not observed in Sitakunda city. However, fatigue, nausea, and vomiting are more common among patients in Dhaka city. Significant heterogeneity of clinical manifestations was present across the three hotspots (p < 0.05 for all). Both confirmed and probable cases shared similar characteristics except muscle ache (p = 0.22) and rash (p = 0.37). Conclusion The clinical profile of chikungunya virus-induced disease displays significant location-related heterogeneity in Bangladesh during a large outbreak. Although the causes of such differences are unclear, improved public and medical personnel education on this condition may lead to earlier diagnosis and treatment.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Chikungunya outbreak in Bangladesh (2017): sociodemographic and clinical characteristics of patients from three hotspots

Amin

Hasan²,

Khan³

et al. 2022

Trop Med Health

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“…7,8,17 More than 30% patients have joint pain more than one months in the outbreak of 2011. 13 This disease is diagnosed by RT-PCR test in first week onset of the disease and IgM test between 5 days to 1 month onset of the disease. 21 Those diagnosis procedures are highly expensive for most of the Bangladeshi people, so low cost diagnosis procedure should be invented for the affected patients.…”

Section: Discussionmentioning

confidence: 99%

“…12 In 2012 an outbreak of chikungunya had been reported in the village of palpara in Tangail district and 364 individuals had been reported with this disease. 13 About 13176 clinically confirmed cases in 17 out of 64 districts were identified by Ministry of Health in April 1, 2017 to September 7, 2017. 14 More than a million of people in Dhaka city were at risk of infection with Chikungunya.…”

Section: Introductionmentioning

confidence: 99%

A Meta-Analysis of the Prevalence of Clinical Manifestations of Chikungunya Virus Disease in Bangladesh

Noor

Hossain

Islam³

2019

Bangla J Med

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Background: Chikungunya is known as a mosquito-borne viral disease. It is transmitted to the human body by infected mosquitoes and caused different symptoms. The main aim of this study was to investigate the percentage of Chikungunya virus disease (CHIKV) patients who would had different clinical features at the acute or sub-acute stage of this disease in Bangladesh. Methodology: In this meta-analysis, PubMed Central and BanglaJOL had been searched. Total 8 eligible studies had been selected for quantitative analysis. The pooled prevalence (PP) was used as effect measure to find the number of patients who would had different symptoms at acute or subacute stage of CHIKV disease. The pooled prevalence and 95% confidence interval (CI) had been calculated using random effects model. To measure the presence of heterogeneity Cochran chi-square test was used and I2 was used to quantify the heterogeneity. Result: This meta-analysis indicated significant association between CHIKV disease patients and fever was [PP: 0.99; p-value = 0.00], joint pain [PP: 0.95, p-value = 0.00], rash [PP: 0.55, p-value = 0.00], joint swelling [PP: 0.38, p-value = 0.001], headache [PP: 0.48, p-value = 0.007], pruritus [PP: 0.37, p-value = 0.001], myalgia [PP: 0.62, p-value = 0.00], co-morbidity [PP: 0.56, p-value = 0.001] at the acute stage of the disease and joint pain persists > 1 month [PP: 0.50, p-value = 0.001] at the subacute stage of this disease. Conclusion: In this meta-analysis ever, joint pain were found as most frequently occurred symptoms at the acute stage of CHIKV disease. Bangladesh J Medicine July 2019; 30(2) : 71-77

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“…It was first isolated from febrile patient of Tanzania in 1955 (Rahman et al, 2017). The disease fall into three phases: Day 1-21 known as acute phase, Day21-90 known as sub-acute phase and from 90 th day onwards called chronic phase (Amin et al, 2017). Chikungunya infection not only causes pain, but also mental health, sleeping disorders and mood swings is observed in patients suffering with chikungunya (Schilte et al, 2013;Ramachandran et al, 2014) 1.…”

Section: Introductionmentioning

confidence: 99%

Medicinal Alternative for Chikungunya Cure: A Herbal Approach

Arora¹,

Tomar²,

Kumari³

et al. 2021

J microb biotech food sci

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Recently a major outbreak of chikungunya affected several countries of the world. In India only 62,628 and 64,057 clinically suspect chikungunya cases in 2017 and 2016 respectively and about 9,175 suspected chikungunya cases through April 2018. A self-remitting febrile viral illness, chikungunya fever caused/spread by Aedes aegypti and Aedes albopictus. The name has been originating from a verb in the Kimakonde language, meaning 'to become contorted' means 'stooped' appearance of joint, signalized by fever and joint pain which can sustain for months or even years in some of the patients. Although many medications are available in the market but the effective treatment against the viral infection is still restricted, due to drug resistance, side effects and toxicity. Focusing the problem, this paper mainly concerns on the cause, transmission of chik virus, and how herbal plants, their active constituents and specific medicinal properties used for relieving symptoms and for cure-providing an alternative way for treating chikungunya. ARTICLE INFO

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Chikungunya

Abstract: not availableJ MEDICINE July 2017; 18 (2) : 92-108

Cited by 3 publications

References 35 publications

Chikungunya outbreak in Bangladesh (2017): sociodemographic and clinical characteristics of patients from three hotspots

Chikungunya outbreak in Bangladesh (2017): sociodemographic and clinical characteristics of patients from three hotspots

A Meta-Analysis of the Prevalence of Clinical Manifestations of Chikungunya Virus Disease in Bangladesh

Medicinal Alternative for Chikungunya Cure: A Herbal Approach

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