Childhood cancer in Southern Iran

Haghighi, Parviz; Mohallatee, E. A.; Nasr, Khosrow; Dezhbakhsh, Fatemeh; Salmasi, Sadegh; Daneshbod, Khosrow

doi:10.1002/1097-0142(197411)34:5<1842::aid-cncr2820340538>3.0.co;2-p

Cited by 22 publications

(13 citation statements)

References 9 publications

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“…All childhood laryngeal carcinomas reported to date have been squamous except for one adenocarcinoma arising from a minor laryngeal salivary gland. 16 The gross and microscopic appearance of squamous carcinoma of the larynx has been well established since the time of V i r~h o w .~~ In children, the lesion is pathologically the same as in adults but may be clinically obscured by associated juvenile papillomatosis.…”

Section: Discussionmentioning

confidence: 99%

“…20 year age group because of the higher incidence for the[15][16][17][18][19][20] year age bracket. For example, Herold and Bockmiihl's population survey in East Germany included 8 patients under 20 years of age, but all were between 15 and 19 years o1d.l' Most large series of laryngeal carcinomas in patients of all ages8.I4 or pediatric malignancies of all ~i t e s , " ' *~' ,~~-~~ include no patient aged 15 years or younger with carcinoma of the larynx.…”

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confidence: 99%

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Carcinoma of the larynx in childhood

Gindhart

Johnston

Chism

et al. 1980

Cancer

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The unusual case of a 12-year-old boy with well differentiated in situ, and focally invasive squamous carcinoma of the larynx is reported, together with a review of the medical literature. In addition to this one, 54 cases of laryngeal carcinoma in children 15 years of age or younger have been reported since 1868. All were squamous except for one adenocarcinoma of a laryngeal minor salivary gland. Carcinoma of the larynx in children parallels that of adults in terms of squamous histology, predominantly vocal cord involvement, pattern of local spread, and response to treatment. However, the incidence of female patients is higher in childhood (40% of childhood cases vs. less than 10% of adult cases), and risk factors, except previous irradiation of papillomas, are rare. Although unusual, carcinoma of the larynx in children is probably more common than thought and the diagnosis should be considered in any case of a child with persistent hoarseness or cough.

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Section: Discussionmentioning

confidence: 99%

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confidence: 99%

Carcinoma of the larynx in childhood

Gindhart

Johnston

Chism

et al. 1980

Cancer

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“…One of the patients with SCC was part of an epidemiologic study for which no specific patient data could be retrieved, and one AC case report was part of a journal’s correspondence section with no further objective validation of histology [27, 28]. These patients were excluded from our study.…”

Section: Resultsmentioning

confidence: 99%

“…The majority of cases reported in the literature consist of SCC [3, 15–27, 30–32] and AC [3–15]. Other malignant esophageal tumors reported in the literature consist of synovial cell sarcoma [33–35], melanoma [36], and “lymphosarcoma” (presumably lymphoma, according to current classifications) [37].…”

Section: Discussionmentioning

confidence: 99%

Esophageal adenocarcinoma and squamous cell carcinoma in children and adolescents: Report of 3 cases and comprehensive literature review

Theilen

Chou

Klimstra

et al. 2016

Journal of Pediatric Surgery Case Reports

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“…1 Since then there have only been 58 such cases reported in the literature.Of these, all were squamous with one exception, an adenocarcinoma arising from a minor salivary gland within the larynx. 2 Of the reported cases where sex was indicated, there appeared to be a male preponderance of 3:2, in contrast with a 4:1 sex ratio found in adult patients. 3 ,4 Furthermore, the age distribution of cases revealed a rising age dependent incidence: seven tumours were found in the one to ve year age group, 14 in the six to 10 year group, and 36 in the 11-15 year olds.…”

Section: Discussionmentioning

confidence: 97%

De novo laryngeal carcinoma in childhood

McDermott¹,

Raj²,

Glaholm³

et al. 2000

J. Laryngol. Otol.

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Numerous factors contribute towards a late diagnosis of laryngeal malignancy in childhood. These include its rarity, the similarity of its early symptoms to those of other benign, common childhood conditions as well as the relative difficulty encountered during paediatric laryngeal examination. We believe that these cases are of sufficient interest when they occur to warrant reporting since the consequences of late diagnosis in these young patients can be serious. We present a case of an 11-year-old boy with advanced squamous cell carcinoma of the larynx (T3N0M0), who was successfully treated with primary total laryngectomy and bilateral selective neck dissections to avoid the potential additional morbidity of radical radiotherapy.

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Childhood cancer in Southern Iran

Cited by 22 publications

References 9 publications

Carcinoma of the larynx in childhood

Carcinoma of the larynx in childhood

Esophageal adenocarcinoma and squamous cell carcinoma in children and adolescents: Report of 3 cases and comprehensive literature review

De novo laryngeal carcinoma in childhood

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