Childhood epidermolysis bullosa acquisita associated with severe dental alterations: A case presentation

Pediatric epidermolysis bullosa acquisita: A review

“…We identified 40 EBA cases of childhood (21 females and 19 males) 1,3‐33 . Of these 40 cases, 7 presented with classical mechanobullous EBA, 31 presented with inflammatory EBA similar to bullous pemphigoid, and 2 cases presented with a mixture of both phenotypes 1,3‐31 .…”

“…We identified 40 EBA cases of childhood (21 females and 19 males) 1,3‐33 . Of these 40 cases, 7 presented with classical mechanobullous EBA, 31 presented with inflammatory EBA similar to bullous pemphigoid, and 2 cases presented with a mixture of both phenotypes 1,3‐31 . EBA age of onset ranged from 2 days old to 16 years old; the patient who presented with EBA at 2 days old was a result of the placental transfer of maternal autoantibodies 21 …”

Inflammatory epidermolysis bullosa acquisita in a 4‐year‐old girl

“…1 usually shows generalized and inflammatory LAD-like skin lesions with frequent severe involvement of mucosal membranes. [4][5][6][7][8] However, childhood EBA generally responds well to conventional therapy, needs no immunosuppressives and shows better prognosis than adult EBA. In a previous study for 14 patients with childhood EBA, five patients each had LAD-like and bullous pemphigoid-like EBA, and four patients had the classical mechanobullous form.…”

“…The latter type resembles other autoimmune blistering diseases, and can be subclassified to bullous pemphigoid‐like EBA, mucous membrane pemphigoid‐like EBA, Brunsting–Perry pemphigoid‐like EBA and LAD‐like EBA . Childhood EBA usually shows generalized and inflammatory LAD‐like skin lesions with frequent severe involvement of mucosal membranes . However, childhood EBA generally responds well to conventional therapy, needs no immunosuppressives and shows better prognosis than adult EBA.…”