Childhood Lichen Planus: A Report of 23 Cases

Nanda, Arti; Al-Ajmi, Hejab; Al‐Sabah, Humoud; Al‐Hasawi, Fowzia; Alsaleh, Qasem A.

doi:10.1046/j.1525-1470.2001.018001001.x

Cited by 85 publications

(121 citation statements)

References 24 publications

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“…The youngest documented case is a threemonth-old child and the reported earliest age at onset has been two weeks. [3][4][5][6]8 Majority of the studies, either the sexes were equally affected or there was marginal male preponderance. 4 Familial LP occurs in 1-2% of all childhood cases and these differ from the classical form clinically, with earlier age at onset, more generalized involvement, more common mucosal involvement and an increased tendency for erosive, ulcerative and linear forms, with prolonged course and frequent relapses.…”

Section: Epidemiologymentioning

confidence: 99%

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Management Of Childhood Lichen Planus

Thapa

Malathi

2016

Nepal J Dermatol Venereol & Leprol

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Childhood lichen planus (LP) is a rare entity, with less than 23% of all cases seen in patients under 20 years of age. LP in childhood is common in subtropical countries such as India. The most common clinical type of LP in Indian children is the classic form. Approximately 115% of patients with LP demonstrate nail involvement, but disease of the nails without skin involvement is rare. LP is diagnosed by history, clinical findings, biopsy results, and, in some cases, features on direct immunofluorescence (DIF). LP tends to have a chronic course. Depending on disease severity, however, LP may respond to a combination of topical or systemic therapies. The response to therapy may be similar to that seen in adults. Moderately potent or super potent steroids are the treatment of choice. Topical steroid can be combined with oral steroid in tapering doses over 2-12 weeks period. This is useful for children with widespread involvement or cutaneous LP lesions associated with significant morbidity. Intralesional steroid is effective for hypertrophic LP unresponsive to topical steroid. Topical steroid in adhesive base used several times a day for several months is a treatment of choice for symptomatic oral LP. Topical steroid in combination with systemic steroid can be given in a tapering dose over 3-6 weeks in very symptomatic cases in early stages. In severe unresponsive cases of both cutaneous and oral LP, oral retnoid are the preferred option. Treatment options for the nail LP in young children are oral steroid given as tapering dose over 4-12 weeks and oral retinoid. Intralesional steroid as nail matrix injection are the third option for older children. Most pediatric patients with LP respond to treatment with full clearance over 1-6 months. Poor response to treatment is a feature of hypertrophic LP and lichen planopilaris. Key words Children, Lichen planus, Nail lichen planus, Oral lichen planus IntroductionLichen planus is a pruritic papulosquamous dermatoses of unknown etiology characterized by presence of violaceous, polygonal, flat-topped papules, affecting the skin, nails and mucous membranes. It usually resolves after a variable period of time leaving behind residual areas of hyperpigmentation.

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Section: Epidemiologymentioning

confidence: 99%

“…Classical LP was the most common variant observed in all the reported studies (42-76%). [3][4][5][6][7][8][9] The second most common variant differed between studies: lichen planus hypertrophicus (12%), actinic LP (11.5%), eruptive LP (13%). Actinic LP is common in tropical and sub-tropical countries including India.…”

Section: Clinical Featuresmentioning

confidence: 99%

Management Of Childhood Lichen Planus

Thapa

Malathi

2016

Nepal J Dermatol Venereol & Leprol

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“…Sharma and Maheshwari reported fifty children with LP; fifteen had oral LP: exclusive lesions on the lips occurred in four; two had labial lesions as well as on the buccal mucosa [13]. Nanda et al observed only 3 patients with lip lesions among 23 children with LP [14]. Publications about "squamous cell carcinoma and oral lichen planus" abound on dental literature; nonetheless, very few deal with labial lesions.…”

Section: General Aspectsmentioning

confidence: 99%

“…The ointment must be applied twice daily, but use may be increased to four times daily until remission or symptomatic relief [21][22][23][24][25][26]. There are a few reports about these drugs on labial LP [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27].…”

Section: Treatmentmentioning

confidence: 99%

Lichen Planus Affecting the Lips

Fern¹,

es²,

Lourenço³

2015

Clin Exp Dermatol Res

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Lichen planus frequently compromises the skin, and the oral mucosa. There is plenty of medical and dental literature about the cutaneous and mucosal lesions of lichen planus, but, comparatively very little has been written specifically about lichen planus compromising the lip vermilion. This structure has a peculiar anatomical and histological architecture, and lichen planus lesions at this site may have some distinct features. This article reviews the recent literature about labial lichen planus in all of its presentations, highlighting some special clinical features that may enable a better diagnosis and differential diagnosis of lip diseases. Besides, personal experience by the authors is added.

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“…It generally starts in the third or fourth decade of life and there is a slight female predilection [2]. The prevalence of LPP among children with lichen planus is low ranging from 2.8 to 4% [3,4].…”

mentioning

confidence: 99%