Childhood Obesity

Abstract

The results of this study demonstrate that childhood obesity is associated with significant changes in myocardial geometry and function, indicating an early onset of potentially unfavorable alterations in the myocardium.

Reference Ranges of Left Ventricular Strain Measures by Two-Dimensional Speckle-Tracking Echocardiography in Children: A Systematic Review and Meta-Analysis

“…74 In this meta-analysis, the location of reported strain value along the strain curve from each eligible study was not a significant determinant of the variation among normal ranges of strain values. Eighteen out of 43 eligible data sets reported the strain time point as “systolic” strain, 8,9,11,13,14,19,21,23,27,28,31,36,38,41,45-48 five reported the strain time point as ESS, 16,17,23,24,48 two reported the “Peak” as the highest strain value at any time point during one cardiac cycle for each patient, irrespective of its location, 20,33 and 20 did not specify the time point location along the strain curve (Table 2). 7,10,12,15,18,22,25,26,29,30,32,34,35,37,39,40,42-44,49 The lack of consistency in reporting of the strain value time point along the strain curve is due in part because only three 47-49 of the eligible studies were published after the recommendations from Voigt et al to report ESS as the “default parameter for the description of myocardial deformation.” 74 In healthy children (with higher heart rates than adults) the systolic and ESS points along the curve may or may not be visually distinguishable, but is most likely clinically insignificant.…”

“…Binnetoglu et al used the same datasets in their two publications 28,69 , and Binnetoglu et al 2013 28 was chosen because it included data on both “global” and “six-segment” strain values. Finally, Sanchez et al 2014 45 and Singh et al 2013 68 used the same control data set and the authors suggested using the manuscript by Sanchez et al 45 in the analysis. …”

Effect of High Intensity Interval Training on Cardiac Function in Children with Obesity: A Randomised Controlled Trial

“…Pediatric obesity is associated with increased all-cause and cardiovascular (CV) mortality 1,2 , independent of adult adiposity 3 . Resting echocardiographic studies show significant systolic and diastolic alterations in cardiac function among children with obesity including lower left ventricular (LV) peak systolic tissue velocity (S'), global longitudinal strain (GLS) and strain rate (SR) when compared to their healthy-weight counterparts [4][5][6][7][8][9] .…”

Arterial Hypertension in the Presence of Overweight and Obesity. The Capabilities of Amlodipine and Lisinopril Combination. Part 1. Features of the Daily Profile of Blood Pressure and Heart Damage as a Target Organ in Patients With Arterial Hypertension in Combination With Overweight and Obesity

“…Так, N. Mangner с соавт. [27] проводили сравнительный анализ функциональных параметров работы сердца, клинико-лабораторных данных у подростков с ожирением и у сопоставимых по полу и возрасту лиц без ожирения. Было выявлено достоверное снижение глобального про-дольного систолического стрейна (ГПС) и циркулярного стрейна в группе пациентов с ожирением.…”