Background: Urinary tract infection (UTI) is common in children. About 7% girls and 2% of boys suffer from symptomatic, culture positive UTI by 6 years of age. These children present with poor feeding, irritability, vomiting, fever, abdominal pain or failure to thrive. Now a days antibiotic resistance is a global problem which hampers appropriate treatment of urinary tract infection in children. This study was done to see clinical profile, common pathogens and their drug sensitivity pattern in UTI. cases were included. History was taken properly. Diagnosis of UTI was confirmed by urinalysis and culture sensitivity (C/S). All informations were recorded in preformed data sheet.Results: Usual presentations of UTI were fever, abdominal pain, vomiting, constipation, urinary complaints, poor feeding, labial adhesion, jaundice, excessive straining. Out of 200 cases 168 were culture positive. Group III age group (> 1year-5 year) showed higher rate of UTI. UP to one year of age males were more affected than female and beyond one-year females were more affected than male. Most common isolated uropathogen was Escherichia coli. Most sensitive drugs for the pathogen were Imipenem and meropenem (89.39%) -Injectable form and nitrofurantoin (73.48 %)-Oral form.Conclusion: Presentation of UTI in case of young infant is different from older children. Clinical suspicion is important for early detection of UTI. Before starting antimicrobial therapy, we must do urinalysis and culture sensitive test to prevent recurrent UTI.