1997
DOI: 10.1097/00006454-199710000-00009
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Childhood vitamin A status and the risk of otitis media

Abstract: In the range of serum vitamin concentrations found in this population, the status of vitamin A and related compounds in children appeared to have no effect on the incidence of otitis media.

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Cited by 12 publications
(10 citation statements)
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“…8,[16][17][18][19] In observational prospective studies, vitamin A deficiency was associated with an increased rate of respiratory infections, 9,20 but not with rate of AOM. 21 In a cross-sectional, follow-up and interventional trial study performed in Thailand in a population with a vitamin A deficiency similar to that of the current study, Bloem et al 10 found a dose-response relationship between respiratory diseases incidence rates in children and mild vitamin A deficiency.…”
Section: Discussionsupporting
confidence: 69%
“…8,[16][17][18][19] In observational prospective studies, vitamin A deficiency was associated with an increased rate of respiratory infections, 9,20 but not with rate of AOM. 21 In a cross-sectional, follow-up and interventional trial study performed in Thailand in a population with a vitamin A deficiency similar to that of the current study, Bloem et al 10 found a dose-response relationship between respiratory diseases incidence rates in children and mild vitamin A deficiency.…”
Section: Discussionsupporting
confidence: 69%
“…The other studies about antioxidant vitamins in the both otitis media [30] and tonsillitis [31,32] demonstrated that the mentioned vitamins were decreased. But, Durand et al [33] did not observe any change in the levels of vitamin A in children with otitis media [33].…”
Section: Discussionmentioning
confidence: 94%
“…In children, in particular, the most common cause of HL is related to middle ear infections. Therefore, studies on the effect of nutrition on middle ear infections have been reported, and these studies suggest that micronutrient status and vitamin deficiency (such as vitamin A or zinc) may cause more frequent inflammation in the middle ear, leading to increased frequency of otitis media, which increases the risk of HL [69,70,71,72,73,74,75,76,77,78,79,80,81,82,83].…”
Section: Evidence That Nutrition Is a Factor Affecting Hlmentioning
confidence: 99%
“…Therefore, many studies concerning middle ear infection related to HL in children have been reported (Table 4). To summarize these studies, deficiencies of single micronutrients and vitamins (such as zinc, vitamin A, iron, and retinol) are associated with mild ear pathologies such as acute or chronic otitis media [69,70,71,72,73,74,75,76]. In addition, multi-micronutrient supplementation studies have reported that the frequency of HL is significantly reduced when these nutrients are supplied sufficiently [77,78,79,80,81,82,83].…”
Section: Studies On Nutrition and Hearingmentioning
confidence: 99%