Chinese herbal compound prescription for Endometriosis

Abstract

Background: Endometriosis (EMT) is one of the common diseases of women of childbearing age. EMT destroys the anatomical structure of the pelvis, which leads to abnormal ovulation and endocrine abnormalities. It also affects embryo implantation and makes patients infertile. Recently, it is confirmed that Chinese medicine also have an excellent clinical efficacy on EMT. Compared with the conventional western medicine treatment, it effectively relieve pain and other concomitant symptoms. Methods and analysis: The following databases will be searched for relevant information before July 2020: PubMed, Embase, Cochrane Library, Web of Science, and CNKI. Major results: the overall effective rate, VAS score. Secondary outcomes: blood serum estradiol (E2), progesterone (P), Follicle-Stimulating Hormone (FSH), adverse events. Data will be collected independently by 2 researchers, and the risk of bias in meta-analysis will be evaluated according to “Cochrane Handbook for Systematic Reviews of Interventions”. All data analysis will be conducted using Review Manager V.5.3. and Stata V.12.0. Results: The curative effect and safety of Chinese herbal compound prescription treatment for EMT patients will be evaluated systematically. Conclusion: The systematic review of this study will summarize the currently published evidence of Chinese herbal compound prescription treatment for EMT to further guide its promotion and application. Ethics and dissemination: The private information from individuals will not be published. This systematic review also will not involve endangering participant rights. Ethical approval is not required. The results may be published in a peer-reviewed journal or disseminated in relevant conferences. Open Science Framework (OSF) registration number: https://osf.io/p5nrk .

TCMM: A Unified Database for Traditional Chinese Medicine Modernization and Therapeutic Innovations

“…TCM is an empirical science based on thousands of years of clinical experience and continues to play a crucial role in disease diagnosis and treatment [1]. In recent years, a wealth of studies [2,3,4,5] have demonstrated that TCM and Western medicine share the same theoretical foundation at the molecular level. Specifically, compounds can treat diseases by regulating the efficacy of targets.…”

Effect assessment of laparoscopy in combination with traditional Chinese medicine decoction in the treatment of endometriosis

“…The treatment of endometriosis with traditional Chinese medicine plays an effective clinical role in alleviating the pain of the disease, slowing the progression of the disease, and preventing the recurrence of the disease after the operation, and has clinical advantages. [6] Modern studies have shown that integrated traditional Chinese and Western medicine has a good clinical effect in the treatment of EMs. However, the existing domestic and foreign literatures on the treatment of EMs with integrated traditional Chinese and Western medicine are numerous and messy, lacking of systematic reviews, and meta-analysis results in insufficient clinical evidence for the treatment of dysmenorrhea by laparoscopy and traditional Chinese medicine.…”

“…There are a large number of domestic literatures that Chinese medicine can effectively treat EMs. The treatment of endometriosis with traditional Chinese medicine plays an effective clinical role in alleviating the pain of the disease, slowing the progression of the disease, and preventing the recurrence of the disease after the operation, and has clinical advantages [6] …”