Chiral separation of several pesticides on an immobilized amylose tris(3-chloro-5-methylphenylcarbamate) column under polar-organic conditions. Influence of mobile phase and temperature on enantioselectivity

Chiral resolution of the insecticide fipronil enantiomers and the simultaneous determination of its major transformation products by high‐performance liquid chromatography interfaced with mass spectrometry

“…Chiralpak IG belongs to the chiral columns of new generation series made by chemical immobilization of the polymeric chiral selector on spherical silica gel particles. It is based on amylose tris(3-chloro-5-methylphenylcarbamate) and has proved to be exceptionally versatile for enantioselective separation and determination of various chiral pesticides, [49][50][51][52][53][54][55][56][57] including the chiral insecticides of phenylpyrazole category. In our experimental approaches, we first privileged the choice on Chiralpak IG column to explore its potential for chiral separation of FIP enantiomers as well as achiral separations for FIP major transformation products.…”

l-Cysteine modified metal–organic framework as a chiral stationary phase for enantioseparation by capillary electrochromatography

“… 12 With the increasing use of pesticide racemates, more harmful chemicals have been introduced into the ecological environment, resulting in various environmental problems. 13 In the pharmaceutical field, nearly half of clinical drugs are chiral and only about 25% are administered as pure enantiomers. 14 One of the isomers of some racemic drugs may have no pharmacological effect or may even have toxic side effects, for example “thalidomide”.…”

Simultaneous Enantiomeric Separation of Carfentrazone-Ethyl Herbicide and Its Hydrolysis Metabolite Carfentrazone by Cyclodextrin Electrokinetic Chromatography. Analysis of Agrochemical Products and a Degradation Study

“…According to the literature, the enantiomeric separation of carfentrazone-ethyl has been carried out by HPLC with UV or MS detection. Using UV detection, values obtained for the enantiomeric resolution for this herbicide ranged from 0.61 to 3.42 in analysis times from 10 to 30 min [ 8 , 9 , 10 , 11 , 12 , 13 ], while with MS/MS detection enantiomeric resolutions close to 4.5 in 4 min [ 5 ] and 1.5 in 35 min [ 14 ] were obtained. The individual enantiomeric separation of carfentrazone-ethyl, carfentrazone and ninety-eight different pesticides was described by HPLC-UV, with resolution values of 2.0 and 2.5, and analysis times of 3.2 min and 7.5 min, for carfentrazone-ethyl and carfentrazone, respectively, at a temperature of 25 °C [ 15 ].…”