Chirale Halbsandwich‐Komplexe von Rhodium(III), Iridium(III), Iridium(I) und Ruthenium(II) mit α‐Aminosäure‐Anionen

Abstract

Metal Complexes of Biologically Important Ligands, LIII. – Chiral Half‐Sandwich Complexes of Rhodium(III), Iridium(III), Iridium(I), and Ruthenium(I1) with a‐Amino Acid Anions The chloro‐bridged metal compounds Cp*(Cl)M(μ‐Cl)2M(Cl)‐Cp* (M = Rh, Ir; Cp* = η5‐C5Me5), (η6‐C6H6)(Cl)

[(η6-C6H3Me3)Ru(L-Ala)Cl]

“…These half-sandwich complexes are interesting in that they contain a chiral metal centre so that if an L-amino acid ligand is used two diastereoisomers may be formed. The ratio of diastereomers varies depending on the amino acid used (Kramer, Polborn, Wanjek, Zahn & Beck, 1990). It has been suggested that intramolecular hydrogen bonding may influence the diastereomer ratio (Sheldrick & Heeb, 1990).…”

Solid-state complexes of poly(L-histidine) with metal chlorides from the first row of thed-block

“…Rey et al 18 studied the complexation equilibria of L-serine and L-leucine with divalent cations of Mg, Ca, Co, Ni, Cu, Zn, Cd, and Pb in (1) aqueous ionic solutions and (2) , all other metal cations form both ML and ML 2 complexes. These results suggest that either pendant groups or coordination crosslinks should form when divalent metal ions are complexed with poly(amino acid)s. 19 While the solution properties of poly(␣-amino acid) complexes with metal ions have been examined, very little has been written about these systems in the solid state. Copper(II) complexes form in solution with the poly(amino acid)s of cysteine, methionine, and cystine (sulfur-containing amino acids); serine, threonine, tyrosine, aspartic acid, and glutamic acid (oxygen as the coordinating group); and lysine, histidine, tryptophan, asparagine, glutamine, and arginine (a coordinating nitrogen).…”

Metallkomplexe mit biologisch wichtigen Liganden, LXXIV [1]. Metallorganische Verbindungen von 2-(3-Thienyl)glycin und dessen Derivaten / Metal Complexes with Biologically Important Ligands, LXXIV [1]. Organometallic Compounds of 2-(3-Thienyl)glycine and Derivatives thereof

“…M etallorganische K om plexe von a-A m inosäuren und P eptiden w urden in d e r letzten Z eit von Sheldrick [4], O ro [5], W erner et al [6 a], G rotjahn [6 b] und von uns [7] untersucht.…”

“…In F ortführung u n serer A rb e ite n [1,7] setzten wir auch D ,L-2-(3-Thienyl)glycin 1 ein. Die nicht proteinogene a-A m in o säu re 1 w urde in Penicilline und C ephalosporine eingeführt [8].…”

“…D erivate von 1 w irken kram pflösend [9] und ein dem Süßstoff A spartam analoges D ipeptid m it 1 besitzt eb en falls eine hohe Süßkraft [10]. Z u 4, 5 [11], 6 [12], 7 [12a, 13], 8 [7a, 14], 9, 10 [4,5,7 a] und 11 [15] analoge K om plexe sind mit an deren a-A m inosäuren bekannt.…”