Chiron

Verma, Ansh; Culbertson, Gabriel; Ramani, Karthik

doi:10.1145/2559206.2581161

Cited by 3 publications

(3 citation statements)

References 14 publications

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“…Researchers have since used this approach to implement health applications [8,30,185] and ubiquitous touch interfaces [43,76,92,143,152]. Sensors have thereby been placed on pants [172,185], belts [43,196], shoes [145], gloves [104,209], and jackets [152]. However, manufacturing techniques and long-term deployments (i.e., surviving wash cycles) remain open research areas for such systems [152].…”

Section: Instrumenting Everyday Objectsmentioning

confidence: 99%

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Finding Common Ground

Große-Puppendahl

Holz

Cohn

et al. 2017

Proceedings of the 2017 CHI Conference on Human Factors in Computing Systems

164

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For more than two decades, capacitive sensing has played a prominent role in human-computer interaction research. Capacitive sensing has become ubiquitous on mobile, wearable, and stationary devices-enabling fundamentally new interaction techniques on, above, and around them. The research community has also enabled human position estimation and whole-body gestural interaction in instrumented environments. However, the broad field of capacitive sensing research has become fragmented by different approaches and terminology used across the various domains. This paper strives to unify the field by advocating consistent terminology and proposing a new taxonomy to classify capacitive sensing approaches. Our extensive survey provides an analysis and review of past research and identifies challenges for future work. We aim to create a common understanding within the field of human-computer interaction, for researchers and practitioners alike, and to stimulate and facilitate future research in capacitive sensing.

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Section: Instrumenting Everyday Objectsmentioning

confidence: 99%

“…Inertial measurement units (IMU) are often paired with capacitive systems in order to reveal more contextual information [65,88], or to provide an additional dimension for user input [114,130,209]. IMUs have also been used to correlate whole-body movements to capacitive sensing data [109,194] and avoid accidental interactions [107].…”

Section: Sensor Fusionmentioning

confidence: 99%

Finding Common Ground

Große-Puppendahl

Holz

Cohn

et al. 2017

Proceedings of the 2017 CHI Conference on Human Factors in Computing Systems

164

View full text Add to dashboard Cite

show abstract

“…The equilibrium structure of S100β was obtained by a long-time-scale molecular dynamics (MD) simulation using GROningen MAchine for Chemical Simulations (GROMACS) 5.0.3 [ 27 ]. Chiron [ 28 ] and YASARA [ 29 ] servers were used to predict the steric clashes, void volume and optimization of the protein. Single Point Charge (SPC) water model was used to solvate the protein without considering hydration shells.…”

Section: Methodsmentioning

confidence: 99%

Investigating the Conformation of S100β Protein Under Physiological Parameters Using Computational Modeling: A Clue for Rational Drug Design

Tiburu

Issah

Darko

et al. 2018

TOBEJ

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Background:Physiochemical factors such as temperature, pH and cofactors are well known parameters that confer conformational changes in a protein structure. With S100β protein being a metal binding brain-specific receptor for both extracellular and intracellular functions, a change in conformation due to the above-mentioned factors, can compromise their cellular functions and therefore result in several pathological conditions such as Alzheimer’s disease, Ischemic stroke, as well as Myocardial Infarction.Objective:The studies conducted sought to elucidate the effect of these physiological factors on the conformational dynamics of S100β protein using computational modeling approaches.Method:Temperature-dependent and protein-cofactor complexes molecular dynamics simulations were conducted by varying the temperature from 100 to 400K using GROMACS 5.0.3. Additionally, the conformational dynamics of the protein was studied by varying the pH at 5.0, 7.4 and 9.0 using Ambertools17. This was done by preparing the protein molecule, solvating and minimizing its energy level as well as heating it to the required temperature, equilibrating and simulating under desired conditions (NVT and NPT ensembles).Results:The results show that the protein misfolds as a function of increasing temperature with alpha helical content at 100K and 400K being 57.8% and 43.3%, respectively. However, the binding sites of the protein was not appreciably affected by temperature variations. The protein displayed high conformational instability in acidic medium (pH ~5.0). The binding sites of Ca2+, Mg2+ and Zn2+ were identified and each exhibited different groupings of the secondary structural elements (binding motifs). The secondary structure analysis revealed different conformational changes with the characteristic appearance of two beta hairpins in the presence of Zn2+and Mg2+.Conclusion:High temperatures, different cofactors and acidic pH confer conformational changes to the S100β structure and these results may inform the design of novel drugs against the protein.

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Design of Interactive Aids for Children’s Teeth Cleaning Habits

Chuko¹,

Chao²,

Tsai³

2020

Adv. sci. technol. eng. syst. j.

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Dental plaque is considered a possible causative agent of major dental diseases. People must develop oral care skills at an early age with family support. This study aims to assist parents and to reduce children's fear while cleaning their teeth. An interactive game challenges children's brushing ability. Arduino modules and software platform were utilized to build a functional prototype. The status of the palm movements identified using a sensing module within brusher. When the cumulative number of swipes exceeds a specified target, the LED moves to the next position. Children became more attentive and adjusted to their corresponding tooth positions according to changes in the hippo's dental light. The average brushing time increased to 226 seconds, with the assistance of the partner. An interactive novelty toothbrush with Bluetooth module was built and evaluated. The contribution of the work is observing children's needs and guide them to brush their teeth from an intimate perspective.

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Chiron

Cited by 3 publications

References 14 publications

Finding Common Ground

Finding Common Ground

Investigating the Conformation of S100β Protein Under Physiological Parameters Using Computational Modeling: A Clue for Rational Drug Design

Design of Interactive Aids for Children’s Teeth Cleaning Habits

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