Choline-phospholipids inter-conversion is altered in elderly patients with prostate cancer

Awwad, Hussain Mohamad; Ohlmann, Carsten-Henning; Stöeckle, Michael; Aziz, Rasul Rafiq; Geisel, Juergen; Obeid, Rima

doi:10.1016/j.biochi.2016.01.003

Cited by 5 publications

(1 citation statement)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, contradictory findings have been reported in different studies. For example, using plasma as the sample, the levels of three sphingomyelin (SM, with a chemical structure similar to PC) species, SM (34:1), SM (36:2), and SM (36:1), were found to be increased in the CaP group 31 ; however, the levels of the same three SM species were found to be decreased in the CaP group in another study 32 . These results indicate that analysis of plasma or serum for CaP biomarker screening is more complicated than that of urine; any systemic or local disorders at other sites may influence the lipid levels in the serum or plasma.…”

Section: Discussionmentioning

confidence: 96%

High level of phosphatidylcholines/lysophosphatidylcholine ratio in urine is associated with prostate cancer

Nakayama

Goto

et al. 2021

Cancer Science

View full text Add to dashboard Cite

Lipid metabolism plays an essential role in cell carcinogenesis by affecting the proliferation, migration, differentiation, and motility of cells. 1-3 Among lipid categories, phospholipids (PLs) and lysophospholipids (LPLs) are the most extensively studied. 4 The expression patterns of several PLs and LPLs reportedly differ in prostate cancer (CaP) cells 5 and tissues. 6 Recently, reports have emerged on trained canines being able to detect CaP by sniffing urine samples from these patients. 7 The odor of the urine perceived by the dogs

show abstract

Section: Discussionmentioning

confidence: 96%