Chondroblastoma: An evaluation of the recurrences and functional outcomes following treatment

Abstract

ObjectiveChondroblastoma is a benign aggressive tumor which needs surgical treatment and has a recurrence rate up to 35%. Extended (aggressive) curettage is the mainstay of treatment and local adjuvants have been reported to decrease the recurrence rate.MethodsThe recurrence rates and the functional results of 14 patients who were treated in our institution and 2 other patients who were treated elsewhere between the years 2004–2016 were evaluated. Seventeen cases (13 male, 3 female; mean age: 17.1 [range: 13 to 32] years) who had been diagnosed, treated and followed up in our hospital between 2004 and 2016 were evaluated in terms of recurrence rates and functional outcomes. The average follow-up period was 41.6 (range: 12 to 132) months.ResultsFive cases of recurrence were observed. Two cases had undergone their primary treatment in another institution. Seven cases were performed curettage alone whereas nine others were administered adjuvant treatments. One of the five recurrence patients was advised to undergo disarticulation. Another was treated with curettage and grafting and the remaining three patients with curettage and cementing. No recurrence was observed in their follow-up period. Their mean MSTS score was 27.3 (range: 4 to 30) over a maximum of 30 points and their functional results were good.ConclusionChondroblastoma is a tumor with high recurrence rates in the post-treatment period. However, good functional outcomes can be achieved with early diagnosis and appropriate treatment even after recurrence.Level of evidence: Level IV, therapeutic study.

10 Years Follow up of Chondroblastoma Treated with Intralesional Curettage: A Retrospective Study

“…Surgical removal of the lesion and bone grafting in a large defect is the standard treatment for chondroblastoma [1,15]. For completely curettage of tumor and avoid recurrence, most authors advised adjuvant physical or chemical inactivation methods, including high-speed burr, electrocauterization, phenol, cryotherapy and ethanol [5,16]. High-speed burr, phenol and ethanol were more widely reported in the previous studies.…”

“…The primary treatment for chondroblastoma is intralesional curettage with or without bone-grafting [4], and some authors preferred chemical or physical adjuvants inactivation to decrease tumor recurrence [5].…”

Outcome of Chondroblastoma Treated With Intralesional Curettage and Autogenous Iliac Bone Graft: A Retrospective Study

“…Surgical removal of the lesion and bone grafting in a large defect is the standard treatment for chondroblastoma [1,2]. For completely curettage of tumor and avoid recurrence, most authors advised adjuvant physical or chemical inactivation methods, including high-speed burr, electrocauterization, phenol, cryotherapy and ethanol [5,18,19]. Ebeid WA et al [4] found a signi cantly lower recurrence rate in patients treated with thorough curettage and high-speed burr.…”

“…However, there is still no study on the comparison of these different adjuvant options and point out the optimal choice. Moreover, adjuvant therapies may cause an extensive tissue damage while killing tumor cells, and should be used carefully, especially for tumors involving the epiphyseal plate [5].…”

“…The primary treatment for chondroblastoma is intralesional curettage with bone grafting in a large defect [4], and some authors preferred chemical or physical adjuvants inactivation to decrease tumor recurrence [5]. The local recurrence rates were obviously different in the literature, which could be as high as 30% [6,7].…”