Chondromyxoid fibroma of the nasal septum: Case report and review of literature

McClurg, Stanley W.; Leon, Marino E.; Teknos, Theodoros N.; Iwenofu, O. Hans

doi:10.1002/hed.21760

Cited by 27 publications

(10 citation statements)

References 57 publications

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“…On CT scan, both tumors are locally aggressive and might demonstrate intra-lesion calcifications, yet, chondrosarcoma is more likely to show calcifications [5] . The presence of intra-lesion calcifications is the radiographic hallmark of chondrosarcoma [7,12] . In our patient, the absence of calcifications on the initial CT scan contributed to the initial misinterpretation of the tumor as a chondromyxoid fibroma.…”

Section: Discussionmentioning

confidence: 99%

“…In our patient, the absence of calcifications on the initial CT scan contributed to the initial misinterpretation of the tumor as a chondromyxoid fibroma. On histopathology, both tumors can be easily misdiagnosed for each other particularly in the case of limited tissue sampling [12,13] . Given the critical anatomical location of the tumor in our case, the true cut biopsy resulted in fragmented specimen which made specific characteristics difficult, moreover, the presence of osteochondroid and fibrovascular fragments with the absence of necrosis, atypia, or mitotic activity favored the diagnosis of benign condition over chondrosarcoma.…”

Section: Discussionmentioning

confidence: 99%

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A diagnostic dilemma: A dorsal spine chondromyxoid fibroma turned out to be chondrosarcoma

Alswerki¹,

Elifranji²,

Hadidi³

et al. 2022

Int. J. Case Rep. Orthop.

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Introduction: Chondrosarcoma is the most common malignant primary tumor of the chest wall. Only a few cases were reported to arise posteriorly from the paravertebral component. Case presentation: In this case report, we present a case of chondrosarcoma, a rare bony tumor which was misdiagnosed with chondromyxoid fibroma in 50 years old male patient. The patient presented with left loin pain with no radiation. The patient underwent radiological imaging and computed tomography guided biopsy, results showed chondromyxoid fibroma, which turned out to be chondrosarcoma on post-operative histopathological examination of the excised tumor. The patient underwent surgical excision of the lesion, with improvement of his symptoms. Conclusion: Despite its rarity, this tumor can be misdiagnosed with chondromyxoid fibroma. Overlapping radiological and histopathological features can make diagnosis difficult with unsatisfactory surgical excision margins. Hence, an extensive pre-operative evaluation and adequate tissue sampling can help avoiding this confusion.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

A diagnostic dilemma: A dorsal spine chondromyxoid fibroma turned out to be chondrosarcoma

Alswerki¹,

Elifranji²,

Hadidi³

et al. 2022

Int. J. Case Rep. Orthop.

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“…Additionally, a chondrosarcoma would be unlikely in the temporal bone[5]. The typical pathological features of CMF are the biphasic arrangement of the myxoid or cartilaginous areas and the peripheral condensation of spindle and stellate cells with eosinophilic cytoplasm imparts a lobular silhouette, which are lacking in chondrosarcoma[17]. In order to decrease the risk of diagnostic error, an accurate diagnosis must be established on the basis of careful correlation of clinical, radiographic, pathological and immunohistochemical findings.…”

Section: Discussionmentioning

confidence: 99%

Chondromyxoid fibroma of the temporal bone: A case report and review of the literature

Zheng

Wang

Dong

2018

WJCC

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BACKGROUNDChondromyxoid fibroma (CMF) is a rare benign bone tumour of cartilaginous origin, which usually affects the metaphysis of the long bone. Involvement of the temporal bone is extremely rare. Patients with CMF in the temporal bone can present some neurological deficits due to involvement of surrounding neural structures.CASE SUMMARYWe present the first case of histopathologically proven CMF originating in the temporal bone and involving the hypoglossal canal in a 40-year-old woman. Hypoglossal nerve paralysis was identified on the cranial nerve examination. The patient underwent surgical excision and was neurologically normal except for mild left facial palsy on 5-mo follow-up examination after surgery. In the current report, the major characteristics and computed tomography/magnetic resonance imaging features of the lesion are discussed. Furthermore, previous literature regarding this pathology is reviewed.CONCLUSIONThe current study presents the first case of temporal bone CMF involving the hypoglossal canal.

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“…1 The rate of recurrence and malignant transformation as stated is 11.5% and 0.7%, respectively. [12]…”

Section: P R O V I S I O N a L L Y A C C E P T E D F O R P U B L I C A T I O Nmentioning

confidence: 99%

Case report of a female child with right nasal chondromyxoid fibroma

et al. 2021

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Chondromyxoid fibroma; a rarely found tumor, contributing <1% of all primary bone neoplasm. We reported a 4-year female child with a 1-year history of nasal obstruction and facial swelling. Large enhanced lesion with amorphous densities spreading into the right cribriform plate and floor of sphenoid sinus, laterallyinto right lamina papyracea, inferolaterally into medial wall of maxillary sinus, posteriorly into nasopharynx and superior aspect of oropharynx was appreciated in CT scan. Mass was excised by Caldwell Luc’s endoscopic medial maxillectomy via the sublabial approach. CMF was confirmed histologically in post-operative biopsy. Keywords: Chondromyxoid fibroma, benign neoplasm, lamina paprycea. Continuous...

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Chondromyxoid fibroma of the nasal septum: Case report and review of literature

Abstract: CMF is a rare, benign neoplasm occasionally occurring in the head and neck. Surgical resection is often curative. CMF must be differentiated from chondrosarcoma, given the substantial differences in treatment.

Cited by 27 publications

References 57 publications

A diagnostic dilemma: A dorsal spine chondromyxoid fibroma turned out to be chondrosarcoma

A diagnostic dilemma: A dorsal spine chondromyxoid fibroma turned out to be chondrosarcoma

Chondromyxoid fibroma of the temporal bone: A case report and review of the literature

Case report of a female child with right nasal chondromyxoid fibroma

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