Chondrosarcoma of the Trachea

Arévalo, Maria T.; Ordi, J; Renedo, G; R, Rami Porta; Oliva, H

doi:10.1159/000194872

Cited by 20 publications

(12 citation statements)

References 5 publications

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“…Squamous-cell carcinoma of the trachea and adenoid-cystic carcinoma are the most frequent malignant tracheal tumours. Recurrent and malignant (sarcomatous) transformation of these chondromas are the most feared complications [4,5].…”

Section: Discussionmentioning

confidence: 99%

Recurrent tracheal mass

Meysman¹,

Noppen

Mey

et al. 2003

Eur Respir J

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In 1994 a 44-yr-old male was admitted for surgical resection of a hard, not painful, nodule which was believed to originate from the isthmus of the thyroid gland. He was known to have mild asthma, treated with inhaled corticosteroids and shortacting b 2 -agonists. His medical record revealed a smoking history of 20 pack-yrs. The patient denied any other symptoms, except the presence of the nodule.On physical examination a hard nodule was felt anteriorly to the trachea. A clear separation with the thyroid gland could not be made.A preoperative computed tomography (CT) scan of the neck revealed a calcified nodule on the midline, adjacent to the trachea ( fig. 1). Laboratory studies demonstrated a euthyroid status.During surgery, the nodule could not be separated from the tracheal cartilaginous ring and a left hemithyroidectomy, with resection of part of the affected cartilaginous ring, was carried out (histology of the nodule in fig. 2a). The tracheal defect was closed with a muscle flap. The patient continued to do well on follow-up examinations f5 yrs postoperatively, without complaints. Repeated bronchoscopy examinations confirmed the tracheal integrity. After 5 yrs the patient was lost to follow-up.Seven years after his first operation the patient reported cough, blood-speckled sputum and dyspnoea on exertion.Physical examination revealed inspiratory wheezes (stridor) over the cervical trachea.Spirometry with flow/volume loop analysis ( fig. 3), bronchoscopy ( fig. 4) and a CT scan of the neck ( fig. 5) were performed. The histology of the resection specimen is shown in figure 2b.

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Section: Discussionmentioning

confidence: 99%

Recurrent tracheal mass

Meysman¹,

Noppen

Mey

et al. 2003

Eur Respir J

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“…Chondrosarcomas of the trachea tend to be slow growing and tend not to metastasize, in contradistinction to chondrosarcomas found elsewhere in the body. 8,10,11,16 Because of this, a proposal to categorize both chondrosarcoma and chondroma of the laryngotracheal region under the term ''cartilaginous tumor'' has even been suggested. 8 The histology for diagnosis of malignancy of cartilaginous tumors involving the long bones and axial skeleton includes features such as cells containing plump nuclei, binucleate cells, and giant cartilage cells with large nuclei or multiple nuclei or with clumps of chromatin.…”

Section: Discussionmentioning

confidence: 99%

Tracheal chondrosarcoma: A case report

1998

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“…Including this case, there are only 18 reported cases of established primary pul monary chondrosarcoma [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16].…”

Section: Discussionmentioning

confidence: 99%

“…Only a few cases have been previously reported [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16]. Primary pulmonary chondrosarcomas are wellcircumscribed, slowly growing tumors which, if not discovered early enough, may spread within the thorax resulting in fatal complications [2,11,15].…”

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confidence: 99%

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Primary Chondrosarcoma of the Left Inferior Lobar Bronchus

Morgenroth¹,

Pfeuffer²,

Viereck³

et al. 1989

Respiration

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A primary chondrosarcoma arising in the left inferior lobar bronchus is described in a 67-year-old man. The symptoms upon admittance were dyspnea, cough with purulent sputum and weight loss. The tumor was removed by pneumonectomy. Eight months later the patient died of massive mediastinal lymph node involvement. While tracheobronchially located primary pulmonary chondrosarcoma tends to remain localized, the peripheral variety tends toward mediastinal lymph node involvement and thoracic metastasis. The treatment of choice is resection in a radical manner, whenever possible.

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Chondrosarcoma of the Trachea

Abstract: A tracheal chondrosarcoma was diagnosed in a 74-year-old man during his workup for a bacterial pneumonia. The clinicopathological features and the evolution of these uncommon tumors are discussed in the present report.

Cited by 20 publications

References 5 publications

Recurrent tracheal mass

Recurrent tracheal mass

Tracheal chondrosarcoma: A case report

Primary Chondrosarcoma of the Left Inferior Lobar Bronchus

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