2008
DOI: 10.1308/147870808x257229
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Choriocarcinoma of the spleen – a rare cause of atraumatic rupture

Abstract: This case report identifies a very rare disease, choriocarcinoma in a male patient, causing another rare entity, an atraumatic rupture of the spleen.

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Cited by 11 publications
(6 citation statements)
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“…1 Atraumatic rupture caused by splenic metastasis of choriocarcinoma is rare, and only six cases have been reported. [7][8][9][10][11][12] Choriocarcinoma is characterized by secretion of high HCG levels. Blood b-HCG levels in our patient were >15,000 mIU/mL, and she had multiple liver and spleen lesions, a suspicious ruptured spleen, and massive hemoperitoneum.…”
Section: Discussionmentioning
confidence: 99%
“…1 Atraumatic rupture caused by splenic metastasis of choriocarcinoma is rare, and only six cases have been reported. [7][8][9][10][11][12] Choriocarcinoma is characterized by secretion of high HCG levels. Blood b-HCG levels in our patient were >15,000 mIU/mL, and she had multiple liver and spleen lesions, a suspicious ruptured spleen, and massive hemoperitoneum.…”
Section: Discussionmentioning
confidence: 99%
“…Spontaneous rupture of splenic metastases with hemoperitoneum is rare and there are only five case reports. 1 2 4 5 6 Table 1 provides a summary of all five case reports. All patients presented with abdominal pain, and only one patient had per vaginal bleeding.…”
Section: Discussionmentioning
confidence: 99%
“… 5 Four patients achieved remission after chemotherapy. One patient died due to progression of the disease, 6 as he could not tolerate chemotherapy due to his poor physical condition. This patient was similar to our patient as she also was unable to tolerate chemotherapy due to her poor clinical condition after recurrent intra-abdominal and intracranial bleeding, thus illustrating the poor prognosis for such patients who cannot be stabilised adequately for initiating chemotherapy.…”
Section: Discussionmentioning
confidence: 99%
“…[2] These hemorrhage sites can be seen in many regions of the body, such as uterus, vagina, lung, kidney, brain, liver, intestines, and spleen. [3–8]…”
Section: Introductionmentioning
confidence: 99%
“…[9] Surgical way, arterial embolization, and radiotherapy with combination chemotherapy are proven as effective methods to stop bleeding. [3–8] The treatment of choriocarcinoma hemorrhage has been improved, but multisite hemorrhage is still very difficult and may suggest poor prognosis. A particularly serious case is the choriocarcinoma syndrome, which consists of hemorrhagic manifestations of metastases in advanced germ cell cancer containing large elements of choriocarcinoma.…”
Section: Introductionmentioning
confidence: 99%