Choroidal blood flow impairment demonstrated using laser speckle flowgraphy in a case of commotio retinae

Hashimoto, Ryuya; Hirota, Asato; Maeno, Takatoshi

doi:10.1016/j.ajoc.2016.08.002

Cited by 18 publications

(11 citation statements)

References 12 publications

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“…Hence, there was absence of any occlusion of the retinal capillaries in the area of grayish discoloration of the retina; in contradistinction, indocyanine green angiography showed a defect in choroidal inflow, probably corresponding to spasm of the choroidal artery, at the CR lesion site in 9 out of 21 patients [8]. Hashimoto et al [10] documented a decrease in the choroidal blood flow using laser speckle flowgraphy in one case of CR. It could be argued that OCTA was done 24 h after trauma and missed the acute spasm of the superficial choroidal circulation, or that the trauma was not very severe to induce a vasogenic response.…”

Section: Discussionmentioning

confidence: 99%

Microvascular Capillary Plexus Findings of Commotio Retinae on Optical Coherence Tomography Angiography

Mansour

Shields

2018

Case Rep Ophthalmol

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Optical coherence tomography (OCT) and histopathology features of commotio retinae (CR) have been established, but alterations of the microvascular macular capillary plexus on OCT angiography (OCTA) has not been previously studied. We present a 46-year-old man who sustained a tennis ball injury to the right eye with visual acuity reduction to 20/30 and grey-white deep macular discoloration, suggestive of CR. Spectral-domain OCT (SD-OCT) showed increased reflectivity and thickness of the ellipsoid zone (junction of photoreceptor inner and outer segments). OCTA revealed no apparent microvascular alterations (right versus left eye) in the foveal avascular zone superficial (0.42 vs. 0.43 mm²) and deep (0.45 vs. 0.44 mm²), superficial foveal capillary density (34.1 vs. 32.6%), and superficial parafoveal capillary density (55.2 vs. 52.2%). Deep macular capillary plexus and choriocapillaris were qualitatively comparable between the two eyes. At 2 months’ follow-up, SD-OCT had normalized. CR is characterized by disruption of the ellipsoid zone without detectable alteration of the capillary plexuses.

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Section: Discussionmentioning

confidence: 99%

Microvascular Capillary Plexus Findings of Commotio Retinae on Optical Coherence Tomography Angiography

Mansour

Shields

2018

Case Rep Ophthalmol

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“…In case 1, we were able to add additional information about the transient breakdown of the blood-retinal barrier (BRB) caused by CGT and its natural course by using multi-modal imaging modalities. There are some reports demonstrating the breakdown of the BRB, especially at the level of the RPE or choroidal blood impairment after CGT [1,6,7]. This breakdown of the BRB may lead to retinal pigment epithelial cell edema and overlying serous retinal detachment [1].…”

Section: Discussionmentioning

confidence: 99%

Multi-modal Imaging Analysis in the Patients with Traumatic Maculopathy

Kang

2019

J Retin

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Purpose: To report the multi-modal imaging characteristics from two cases of traumatic maculopathy and their visual outcomes. Case summary: (Case 1) A 37-year-old male patient visited the ophthalmology clinic after a contusion to the left eyeball. The best-corrected visual acuity (BCVA) in the left eye was 20/100 by the Snellen visual acuity chart. Fundus examination showed yellow-gray-colored retinal edema along the superotemporal vascular arcade and macula in the left eye. Spectral domain optical coherence tomography (SD OCT) revealed subretinal fluid with diffuse ellipsoid zone disruption. On fluorescein angiography (FA), the edematous retinal lesion showed hypofluorescence with stippled hyperfluorescent spots in the early phase followed by diffuse leakage in the late phase. After 1 week, the subretinal fluid completely resolved. After four months, BCVA improved to 20/20, and the ellipsoid zone was nearly recovered. (Case 2) A 47-year-old male patient visited the ophthalmology clinic after a contusion to the left eyeball. The BCVA of the left eye was count finger. Foveal depigmentation was noted on fundus examination. Foveal detachment with diffuse disruption of the ellipsoid zone was noted by SD OCT. On FA, dye pooling in the fovea was shown throughout the examination. After 5 days, the foveal detachment completely resolved, and BCVA was 20/200. After 5 months, BCVA was 20/50, and SD OCT showed partial recovery of the ellipsoid zone. Conclusions: Multi-modal imaging analysis seems to be useful for differentiating the characteristics of traumatic maculopathy and predicting visual outcomes.

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“…14 OPP was calculated from measurements of the patient's IOP and blood pressure, as described earlier. 7 , 8 …”

Section: Methodsmentioning

confidence: 99%

“…Laser speckle flowgraphy (LSFG-NAVI®, Softcare Co. Ltd., Fukuoka, Japan) is a non-invasive quantitative method that is very useful for measuring and assessing choroidal blood flow (CBF) 7 , 8 and pulse waveforms 9 based on the changes in the speckle pattern of the reflection of laser light from the fundus photo. 10 The mean blur rate (MBR) is a parameter of blood flow speed.…”

Section: Introductionmentioning

confidence: 99%

Changes in choroidal circulation and pulse waveform in a case of pregnancy-induced hypertension with serous retinal detachment

Yata

Hashimoto

Masahara

et al. 2020

American Journal of Ophthalmology Case Reports

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Purpose We aimed to examine the changes in choroidal blood flow (CBF), choroidal pulse waveform, and central choroidal thickness (CCT) in a case of pregnancy-induced hypertension (PIH) using laser speckle flowgraphy (LSFG) and enhanced depth imaging optical coherence tomography (EDI-OCT) before and after treatment with antihypertensive drugs. Observations A 24-year-old Japanese woman diagnosed with PIH presented with complaints of worsening and blurred vision in the right eye. Funduscopic findings at the initial visit showed serous retinal detachment (SRD), retinal hemorrhage, and arterial tortuosity. The LSFG color map showed a warm color. Macular mean blur rate (MBR), which is an index of relative blood flow velocity, in both eyes was high, along with choroidal thickening. Blowout time (BOT), which indicates the rate of time in which the MBR is greater than half the amplitude during one heartbeat, was low and acceleration time index (ATI), which represents the time-to-peak of MBR, was high. Several weeks after treatment with antihypertensive drugs, the CBF and ATI gradually decreased with regression of the SRD and thinning of the CCT. On the other hand, BOT gradually increased after treatment, showing a significant decrease in vascular resistance. Ocular perfusion pressure decreased after treatment because of the reduction in blood pressure. Conclusions and Importance LSFG might reveal choroidal overperfusion and increased vascular resistance, along with SRD and choroidal thickening, in a patient with PIH with reversal after treatment with antihypertensive drugs. These findings demonstrate the importance of evaluation of ocular blood flow and vascular resistance in women with PIH in order to routinely assess the clinical and systemic condition.

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Choroidal blood flow impairment demonstrated using laser speckle flowgraphy in a case of commotio retinae

Cited by 18 publications

References 12 publications

Microvascular Capillary Plexus Findings of Commotio Retinae on Optical Coherence Tomography Angiography

Microvascular Capillary Plexus Findings of Commotio Retinae on Optical Coherence Tomography Angiography

Multi-modal Imaging Analysis in the Patients with Traumatic Maculopathy

Changes in choroidal circulation and pulse waveform in a case of pregnancy-induced hypertension with serous retinal detachment

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