PurposeWe aimed to examine the changes in choroidal blood flow (CBF) and central choroidal thickness (CCT) in children with anisohypermetropic amblyopia using laser speckle flowgraphy (LSFG) and enhanced depth imaging optical coherence tomography (EDI-OCT).ObservationsThe patients were both 6-year-old Japanese male children with complaints of worsening right visual acuity and were diagnosed with anisohypermetropic amblyopia. The decimal best-corrected visual acuities (BCVAs) in cases 1 and 2 were both 0.5. In both cases, LSFG results demonstrated CBF impairment in amblyopic eyes compared with fellow eyes. EDI-OCT results also showed that the CCTs of amblyopic eyes were greater than those of fellow eyes at the initial visit. Several months after the first visit, the decimal BCVAs in both cases had improved to 1.0 because of treatment. Further, the CBF gradually increased along with a decrease in the CCT of the amblyopic eye. The axial lengths and spherical powers of the amblyopic eyes in the two cases were not different during follow-up.Conclusions and importanceWe have determined the changes in CBF and CCT in two children with anisohypermetropic amblyopia for the first time. CBF impairments may be involved in the pathogenesis of anisohypermetropic amblyopia, and LSFG may be useful in examining CBF in pediatric anisohypermetropic amblyopia.

PurposeTo report the time course of choroidal blood flow (CBF) in a commotio retinae case using laser speckle flowgraphy (LSFG).ObservationsA 58-year-old Japanese man with complaints of worsening left visual acuity after blunt eye trauma was diagnosed with commotio retinae. A funduscopic examination showed macular opacity, and LSFG results demonstrated CBF impairment in the affected eye.Optical coherence tomography also showed disruption of the photoreceptor outer segment. Seven months after the initial visit, CBF was significantly increased, along with improvement in the photoreceptor outer segment.Conclusionand importance: We revealed CBF impairment in a case of commotio retinae for the first time. CBF impairment may be involved in the pathogenesis of commotio retinae, and LSFG may be useful for examining CBF in commotio retinae.