Choroidal expansion during the water drinking test

Abstract

There was a significant increase of OPA and ChT measurements followed by an IOP rise during the WDT. Increased choroidal volume due to hemodynamic forces may be enrolled in the mechanism of IOP elevation during this stress test.

Choroidal Thickness in Open-Angle Glaucoma Measured by Spectral-Domain Scanning Laser Ophthalmoscopy/Optical Coherence Tomography

“…Similarly, Ehrlich et al [20] did not find a significant difference in peripapillary choroidal thickness in patients with and without open-angle glaucoma using SD-OCT. In agreement with previous investigations [1,2,16,21,22,23,24], we found increased choroidal thickness in glaucomatous eyes versus healthy eyes, which was probably due to vascular events in the uvea that caused the open-angle glaucoma.…”

“…They hypothesized that the reduction in the number of vessels in the choriocapillary would lead to a decrease in the rate of blood flow in a unit of time, and that it would also cause an increase in the gradient of perfusion pressure in the still permeable vessels. An increase in the pressure gradient would lead to a rise in IOP owing to a ductal enlargement and a subsequent increase in the choroidal layer [1,16]. Using B scan echography, De Moraes et al [16] found increased choroidal thickness in glaucomatous eyes during the water drinking test.…”

“…An increase in the pressure gradient would lead to a rise in IOP owing to a ductal enlargement and a subsequent increase in the choroidal layer [1,16]. Using B scan echography, De Moraes et al [16] found increased choroidal thickness in glaucomatous eyes during the water drinking test. They reported a transient IOP rise preceded by an increase in the ocular pulse amplitude associated with choroidal thickness.…”

“…They reported a transient IOP rise preceded by an increase in the ocular pulse amplitude associated with choroidal thickness. This may explain, in part, the IOP elevation during this test [16]. A study conducted with the partial coherence interferometric technique suggested that choroidal thickness is probably a dynamic parameter influenced by oscillations in IOP or the cardiac cycle [8].…”

“…The choroid is a highly vascular structure with blood flow and thickness that varies in relation to such disorders as elevated intraocular pressure (IOP) [1,16]. Formerly, choroidal thickness was assessed based on histology, ultrasonography and partial coherence interferometry results [1,2,8].…”