Choroidal osteoma with choroidal excavation and associated neovascular membrane: An OCT-angiography study

Clemente-Tomás, R.; Cerdà-Ibáñez, M.; Gargallo-Benedicto, A.; Marín-Lambíes, C.; Manfreda-Domínguez, L.; Duch-Samper, A.

doi:10.1016/j.oftale.2018.03.008

Cited by 2 publications

(3 citation statements)

References 3 publications

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“…Therefore, within this population, CNV has a relatively high occurrence and is a significant cause for visual morbidity and may portend a poor long-term visual prognosis [2]. Many reported cases of CNV and associated subretinal fluid in CO have resolved with a series of up to four anti-VEGF injections [4][5][6][7]. Our case required ten monthly injections of ranibizumab suggesting a more aggressive or refractory secondary CNV than those previously reported.…”

Section: Discussionmentioning

confidence: 57%

“…OCT-A imaging of CNV secondary to CO has now been described in patients who have been responsive to bevacizumab or ranibizumab [4][5][6][7]. Our current case presents the longest follow-up in the literature of treatment with anti-VEGF and documentation with OCT-A.…”

Section: Introductionmentioning

confidence: 70%

“…CNV was seen most commonly in tumors with an irregular surface or overlying hemorrhage. Optical coherence tomography angiography (OCT-A) has been shown to be effective in evaluating CNV in patients with CO and those treated with anti-vascular endothelial growth factor (anti-VEGF) therapy [3][4][5][6][7].…”

Section: Introductionmentioning

confidence: 99%

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The Role of Optical Coherence Tomography Angiography in Ranibizumab-Treated Choroidal Neovascularization in Choroidal Osteoma

Carroll¹,

Zhang²,

Jampol³

et al. 2020

Case Rep Ophthalmol

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In this study, we report the initial evaluation of choroidal neovascularization (CNV) secondary to choroidal osteoma and subsequent response to anti-vascular endothelial growth factor (anti-VEGF) treatment monitored with optical coherence tomography angiography (OCT-A). A 38-year-old female presented with an initial visual acuity of 20/150 in the left eye. Clinical examination revealed a choroidal osteoma. OCT demonstrated both subretinal and intraretinal fluid. OCT-A was performed and showed CNV. A course of ten treatments with ranibizumab showed an improvement of visual acuity to 20/30-3, improvement of subretinal and intraretinal fluid, as well as attenuation of CNV. Our report demonstrates OCT-A as a useful tool for both initial evaluation of CNV and following treatment response to anti-VEGF therapy.

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