Chromatography coupled with inductively coupled plasma atomic emission spectrometry and inductively coupled plasma mass spectrometry. A review

Comparison of Derivatization Methods for the Determination of Butyl- and Phenyl-tin Compounds in Mussels by Gas Chromatography

“…Most of the analytical methods developed for the separation and quantitation of the different organotin compounds are based on the use of hyphenated techniques using liquid or gas chromatography. 4,5 Gas chromatography has been mostly used, because of its high resolving power and an easy coupling to sensitive and selective detectors, e.g. AAS, 6 AES, 7 FPD 8 and MS. 9 Due to the low volatility of the organotins, a derivatization reaction is required when a technique based on gas chromatography is going to be used.…”

The Contribution of Inductively Coupled Plasma Mass Spectrometry to Biomedical Research

“…Among the possible solutions under development, direct coupling through an in-lab modified Meinhardh (28), an ultrasonic (29), and a micro-flow (30) ence of buffer and buffer pH on metallothionein determination by CZE-ICP-MS, using an interface developed in their laboratory (32). The first report of elemental speciation by HPLC-ICP-MS was published in 1986 (33) and technical aspects and applications of HPLC-ICP-MS have been recently reviewed (6,27,(34)(35)(36)(37). Coupling ICP-MS with HPLC is a relatively easy task as flow rates commonly used in both instruments are compatible.…”

“…These considerations may limit at present the application of ICP-MS in routine clinical laboratories, but do not diminish the considerable potential offered by this technique for research in biomedicine. Reviews have appeared in the recent literature covering various aspects of the applications of ICP-MS in biomedicine (5)(6)(7)(8), but work in this field is progressing at a fast pace. Recently, as a further development of ICP-MS instrumentation, High Resolution-Inductively Coupled Plasma-Mass Spectrometers (HR-ICP-MS) have become available (9), which offer higher resolution with little or no reduction of LODs, and thus the potential to overcome most of the polyatomic interferences affecting ICP-MS determinations in complex matrices.…”

Capillary electrophoresis‐inductively coupled plasma‐mass spectrometry: A report on technical principles and problem solutions, potential, and limitations of this technology as well as on examples of application

“…Already many years ago, Barnes [23] overviewed the potential of ICP-based detectors when combined with flow-injection analysis, direct sample introduction and vaporization systems, and chromatographic techniques [23]. The big advantage of ICP-MS is given by its multielemental capability and sensitivity [24], thereby gaining isotopic and elemental information. The ionization source is an ICP, the temperature of which is around 5000 -9000 K. The plasma, mostly of Ar, is formed within a quartz torch, made up of three concentric quartz tubes, with the gas flowing at different rates through each tube.…”