“…However, the application of ICP-MS to biological fluid and tissue samples has been limited to the investigation of elements present in ultratrace amounts (38,39 ). ICP-MS analyses of biological samples need not be limited to analytes that include metal elements.…”
“…However, the application of ICP-MS to biological fluid and tissue samples has been limited to the investigation of elements present in ultratrace amounts (38,39 ). ICP-MS analyses of biological samples need not be limited to analytes that include metal elements.…”
“…ICPM-8500 (Shimadzu, Kyoto, Japan) was used to determine values for eight different metals, including Al, Cr, Mn, Fe, Co, Cu, Zn and Mo [14][15][16]. The metals contents were used calibration curve method, and the detection limit was 10 mg/kg.…”
Section: Determination Of Trace Metals By Icp-msmentioning
“…At present, Se status is assessed by means of the determination of either total Se or glutathione peroxidase. However, the discovery of a new selenoprotein (selenoprotein P) in rat (39,40) and human plasma (41) has stimulated research in this field to define the role and significance of this species. As analytical methodologies for the dosage of selenoprotein P are developed, ranging from various chromatographic techniques to radioimmunoassay (42)(43)(44)(45)(46)(47)(48), selenoprotein P has been shown to account for a larger fraction of total Se than glutathione peroxidase (48,49) and investigations on its role in human Se metabolism are in progress (50 -55).…”
Section: Contribution Of New Methodologies To the Diagnosis Of Trace mentioning
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