Chromoblastomycosis caused by Fonsecaea monophora in Mexico

Campos-Macías, Pablo; Arenas, Roberto; Aquino, Caren J.; Romero-Navarrete, Marina; Martínez‐Hernández, Fernando; Martínez-Chavarría, Luary C.; Xicohtencatl‐Cortes, Juan; Hernández‐Castro, Rigoberto

doi:10.1016/j.mycmed.2021.101114

Cited by 4 publications

(5 citation statements)

References 22 publications

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“…was discovered using molecular analysis of strains taken from patients. Cultivation and DNA sequencing from culture veri ed the identity (Campos-Macias et al, 2021).…”

Section: Search Strategy and Inclusion Criteriamentioning

confidence: 94%

“…is the most common pathogen underlying CBM (Queiroz-Telles et al, 2017;Santos et al, 2021). At present, the Fonsecaea clade contains the clinically relevant species F. pedrosoi (Belda et al, 2020;de Andrade et al, 2020;Santos et al, 2007;Singh et al, 2006;Vicente et al, 2008), F. monophora (Campos-Macias et al, 2021), F. nubica (You et al, 2019) and F. pugnacius (Bombassaro et al, 2020). Infection by Fonsecaea spp.…”

Section: Introductionmentioning

confidence: 99%

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Evolutionary Relationships, Phylogeographic Patterns, and a Hypothesis for Air- and Sea-driven Global Spread of Chromoblastomycosis by Etiological Fonsecaea Agents

Wang

Hao²,

Cai

et al. 2022

Preprint

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Fonsecaea spp. is the most common pathogen underlying chromoblastomycosis. However, many aspects of its evolutionary history are not fully understood, and a timescale for its diversification is lacking . Here, we propose, explain, and validate the evolutionary relationships, transmission routes, and modes of transmission among pathogenic species of the genus Fonsecaea . we investigated the sequences of a total of 510 intra-ribosomal transcribed regions and 485 reported cases of eight strains of the genus Fonsecaea , that have spread epidemically worldwide, persisted, and diversified over 38.27 million years. This period coincides with the diversification of many filamentous fungi, and this evolution explains the diversity and origin of pathogenic species of Fonsecaea spp . , as well as the possible transmission routes. Fonsecaea pedrosoi originated in the Atlantic Ocean near Brazil, F. monophora originated in the Pacific Ocean near southern China, and F. nubica originated in the Indian Ocean near Madagascar. F. pugnacius originated and is endemic in the Atlantic Ocean near Brazil. We proposed the hypothesis that non-pathogenic environmental strains in the environment ( Fonsecaea brasiliensis , F. multimorphosa , F. minima , and F. erecta ) evolved into pathogenic strains ( F. pedrosoi , F. pugnacius , F. nubica , and F. monophora ) and spread globally with global tropical cyclone and ocean currents pathways. F. multimorphosa is potentially infectious to humans. The present study’s results will greatly facilitate the prevention, treatment, and cure of Fonsecaea infections and give insight and reference to researchers in the field of fungal research, especially other pathogenic fungi and environmental fungi.

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“…was discovered using molecular analysis of strains taken from patients. Cultivation and DNA sequencing from culture veri ed the identity (Campos-Macias et al, 2021).…”

Section: Search Strategy and Inclusion Criteriamentioning

confidence: 94%

Section: Introductionmentioning

confidence: 99%

Evolutionary Relationships, Phylogeographic Patterns, and a Hypothesis for Air- and Sea-driven Global Spread of Chromoblastomycosis by Etiological Fonsecaea Agents

Wang

Hao²,

Cai

et al. 2022

Preprint

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“…The protein coding genes may achieve better identification in certain fungal groups; however, their amplification and sequencing efficacies limit their use as a universal marker [40,41]. For CBM agents, ITS barcoding accurately differentiates the four species of the genus Fonsecaea implicated in CBM: Fonsecaea pedrosoi, Fonsecaea monophora, Fonsecaea nubica, and Fonsecaea pugnacius and differentiates them from Cladophialophora carrionii [2,[36][37][38][42][43][44][45]. The nucleotide alignment of the ITS sequences enabled us to identify six Cladophialophora carrionii and 24 Fonsecaea nubica cases in our study ( [2] and unpublished data).…”

Section: Dna Sequencingmentioning

confidence: 99%

“…In addition, molecular diagnosis of mycetoma has been recently and superbly reviewed in [32]. DNA extraction from fungal colonies can be performed either using in-house (including glass bead beating and chloroform-isoamyl alcohol) [33][34][35] or commercially available protocols, such as the Qiagen (QIAGEN, Venlo, The Netherlands) [2,[36][37][38].…”

Section: Introductionmentioning

confidence: 99%

Molecular Diagnosis of Two Major Implantation Mycoses: Chromoblastomycosis and Sporotrichosis

Maubon

Garnaud

Ramarozatovo³

et al. 2022

JoF

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Chromoblastomycosis and sporotrichosis are the two main implantation mycoses that are now recognized as fungal neglected tropical diseases (NTDs). Their laboratory diagnosis mainly relies on direct microscopy, histopathology, and identification of the fungus by culture. However, to be appropriately used, these techniques require mycological expertise that is not widely available and may be absent in peripheral health care facilities in endemic areas. In addition, they lack sensitivity and specificity, and the culture for isolation and identification can have a long time-to-results period. Molecular methods, including matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), have been developed in well-equipped reference laboratories. They greatly improve the rapidity and accuracy of diagnosis; in particular, for species identification. Recently, PCR and sequencing have paved the way for more user-friendly point-of-care tests, such as those based on LAMP or RCA technologies, which can be used in basic healthcare settings and even in field consultations.

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“…The most accurate and probably frequently used approach of diagnosis involves identifying pigmented fungi from brain tissue histopathology or culture. The most effective course of treatment involves surgical resection and prompt administration of a combination of antifungal medications [ [4] , [5] , [6] ]. Many dematiaceous fungal species have been linked to CP, with Cladophialophora bantiana and Rhinocladiella mackenziei accounting for roughly 50 % and 15 % of CP cases, respectively [ 7 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

A rare case of cerebral phaeohyphomycosis caused by Fonsecaea species in a renal transplant patient

Qureshi,

Absar,

Nasser

et al. 2024

Medical Mycology Case Reports

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Chromoblastomycosis caused by Fonsecaea monophora in Mexico

Cited by 4 publications

References 22 publications

Evolutionary Relationships, Phylogeographic Patterns, and a Hypothesis for Air- and Sea-driven Global Spread of Chromoblastomycosis by Etiological Fonsecaea Agents

Evolutionary Relationships, Phylogeographic Patterns, and a Hypothesis for Air- and Sea-driven Global Spread of Chromoblastomycosis by Etiological Fonsecaea Agents

Molecular Diagnosis of Two Major Implantation Mycoses: Chromoblastomycosis and Sporotrichosis

A rare case of cerebral phaeohyphomycosis caused by Fonsecaea species in a renal transplant patient

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