1988
DOI: 10.1016/0165-1218(88)90038-9
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Chromosomal aberration and sister-chromatid exchange frequencies in peripheral blood lymphocytes of a large human population sample

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Cited by 197 publications
(67 citation statements)
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“…This finding is in agreement with previously reported data on the age-related incidence of chromosomal damage among control populations. Indeed, while some authors did not find a significant increase of CAs frequency with age (Anderson et al, 1993;Kaˇsuba et al, 1995), others reported a significant correlation between age and SCEs in peripheral blood lymphocytes (Bolognesi et al, 1997;Bender et al, 1998;Stephan and Pressl, 1999). The lack of a similar pattern among technicians could be due to an increased incidence of the chromosomal damage induced by professional exposure among younger individuals.…”
Section: Discussionmentioning
confidence: 96%
“…This finding is in agreement with previously reported data on the age-related incidence of chromosomal damage among control populations. Indeed, while some authors did not find a significant increase of CAs frequency with age (Anderson et al, 1993;Kaˇsuba et al, 1995), others reported a significant correlation between age and SCEs in peripheral blood lymphocytes (Bolognesi et al, 1997;Bender et al, 1998;Stephan and Pressl, 1999). The lack of a similar pattern among technicians could be due to an increased incidence of the chromosomal damage induced by professional exposure among younger individuals.…”
Section: Discussionmentioning
confidence: 96%
“…Esses achados estão de acordo com os observados por vários autores (Bender et al, 1988;Galloway et al, 1986;Hedner et al, 1982;Margolin & Shelby, 1985), enquanto que outros autores não encontraram nenhum efeito com relação ao sexo (Anderson et al, 1991).…”
Section: Discussionunclassified
“…Also consistent with our findings, Jin and colleagues [38] reported non-linear transcription responses after low dose exposures. Non-linear dose-response relationships have previously been reported at higher doses for non-genomic endpoints, such as chromosome aberrations [57] and cell killing [58] after exposures to low-LET radiation, and more recently in a more limited study of low dose effects on transcript levels [35,37].…”
Section: Shape Of the Transcript Dose Response Curvesmentioning
confidence: 93%