CHROMOSOMAL REARRANGEMENTS DO NOT SEEM TO AFFECT THE GENE FLOW IN HYBRID ZONES BETWEEN KARYOTYPIC RACES OF THE COMMON SHREW (<i>SOREX ARANEUS</i>)

Horn, Adolf Heinrich; Basset, Patrick; Yannic, Glenn; Banaszek, Agata; Бородин, П. М.; Bulatova, N. Sh.; Jadwiszczak, Katarzyna A.; Jones, Roy E.; Polyakov, Andrey; Ratkiewicz, Mirosław; Searle, Jeremy B.; Щипанов, Н. А.; Zima, Jan; Hausser, Jacques

doi:10.1111/j.1558-5646.2011.01478.x

Cited by 63 publications

(53 citation statements)

References 51 publications

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“…Conversely, divergence estimates in shrew populations differing by Rb fusions produced mixed results. In two parapatric species of shrews, molecular markers on rearranged chromosomes showed higher divergence levels than those on collinear chromosomes (Basset et al, 2006), whereas such differences were not observed among several chromosomal races of the common shrew (Horn et al, 2011). In addition to the possible lack of resolution due to the imprecise localization of the markers in shrews, these discrepancies highlight confounding difficulties in disentangling the relative contributions of reduced gene flow, ancestral polymorphism and selection at linked sites (Nachman and Payseur, 2012), particularly in closely related taxa (that is, races vs species).…”

Section: Effect Of Rb Heterozygosity On Gene Flowmentioning

confidence: 81%

Reduced recombination patterns in Robertsonian hybrids between chromosomal races of the house mouse: chiasma analyses

2014

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The recombination suppression models of chromosomal speciation posit that chromosomal rearrangements act as partial barriers to gene flow allowing these regions to accumulate genetic incompatibilities, thus contributing to the divergence of populations. Empirical and theoretical studies exploring the requirements of these models have mostly focused on the role of inversions. Here, the recombination landscape of heterozygosity for Robertsonian (Rb) fusions is investigated in the house mouse. Laboratory-bred F1 males and females between highly differentiated races from Tunisia (Rb: 2n ¼ 22, Standard, St: 2n ¼ 40) were produced in which all Rb fusions are present as trivalents in meiosis. Recombination patterns were determined by the analysis of chiasmata and compared with previous data on the Tunisian parental mice. A comparative analysis was performed on wild-caught male mice spanning the hybrid zone between two Italian races (2n ¼ 40, 2n ¼ 22). The results showed that the chiasma characteristics of both male and female Tunisian F1 and Italian hybrids clearly differed from those of Rb and St mice. Not only was the mean chiasma number (CN) intermediate between those of the parental mice in both geographic samples, but the distribution of chiasmata along the chromosomal arms of the F1 showed a distinct mosaic pattern. In short, the proximal region in the F1 exhibited a reduced CN similar to that observed in homozygous Rb, whereas distal regions more closely matched those in St mice. These results suggest that Rb rearrangements (homozygous or heterozygous) reduce recombination in the proximal regions of the chromosomes supporting their potential role in recombination-mediated speciation models.

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Section: Effect Of Rb Heterozygosity On Gene Flowmentioning

confidence: 81%

Reduced recombination patterns in Robertsonian hybrids between chromosomal races of the house mouse: chiasma analyses

2014

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“…The idea of discontinuity between local populations is in good agreement with microsatellite studies. Significant population structuring of the common shrew was noted in many studies Lugon-Mouline et al, 1999Andersson, 2004;Horn et al, 2012). Magnitude of F st was not different, notably, in comparisons of samples of the same race and between different races.…”

Section: Discussionmentioning

confidence: 84%

“…According to Jiggins and Mallet (2000), bimodality is evidence of "a route to speciation" or is a witness of inhibition of gene flow between contacting forms. Also almost all authors show that intra-racial structuring is significant, and sometimes it is greater than interracial structuring (Lugon-Mouline et al, 2000;Ratkievicz et al, 2002;Horn et al, 2012). We suppose that the paradoxical results of estimations with using various kinds of frequency markers versus chromosomal diversity could be explained by a remarkable impediment of gene flow not only between races but also between populations within races.…”

Section: Introductionmentioning

confidence: 87%

“…Also, large molecular variability within races was found in a number of studies (Lugon-Mouline et al, 2000;Ratkiewiz et al, 2002;Andersson, 2004). Both the level of complexity of hybrids and the type of chromosomes had no effect on genetic distance between races, as it was measured with using microsatellite alleles (Horn et al, 2012). Lack of correspondence of genetic differences that have been measured by various sorts of markers with racial differentiation might look like evidence of unlimited gene flow across the hybrid zones (Frykman et al, 1983;Frykman & Bengtsson, 1984;Searle, 1985Ratkievicz et al, 2003).…”

Section: Introductionmentioning

confidence: 99%

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Intra-species structuring in the common shrew Sorex araneus (Lipotyphla: Soricidae) in European Russia: morphometric variability could give evidence of limitation of interpopulation migration

Щипанов¹,

Voyta²,

Бобрецов³

et al. 2014

Rus.J.Theriol.

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ABSTRACT. The shape of the skull, mandible, and first lower molar (m1) in 10 geographical samples from four chromosomal races of two karyotypic groups were studied using geometric morphometrics. Discriminant analysis with cross-validation was used to test the accuracy of classifications of specimens using skull shape. The percentage of correct classifications attributed to race varied from 61.8% to 89.5% and ranged from 51.6% to 82.3% for geographical samples. The structuring between races, as measured with Q st (this metric is analogous to F st , and the latter is used as a measure of genetic disparity between samples), was less than population-level structuring both within and between races. Variance between karyotypic groups in skull size, mandible, and molar shape was greater than between races. In skull shape, the variance was smaller as compared to the inter-racial level without larger "mountain" samples and greater when the entire set of samples was estimated. Interpopulation differences in all census characteristics were the most prominent. The magnitude of Q st in interpopulation estimations was similar both among populations of the same race and among populations of different races. Lack of correlation of Q st level with geographical distance between samples was found both in size and shape of the skull, mandible, and first lower molar. The significant difference between populations within a race was regarded as evidence of limitation of interpopulation migration. Each pair of geographic samples has a unique set of differentiating features. The stochastic variability of traits between the local samples, irrespective of race, is interpreted as evidence of genetic drift within partly isolated local populations. Diminishing differences between races could be a consequence of reabsorbing those stochastic morphological differences back into the metapopulations. The greater level of phenotypic differentiation between karyotypic groups compared to races is interpreted as a greater amount of time elapsed since the time of common ancestry.

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“…In the case of NovosibirskTomsk hybrid zone we would also expect strongly restricted gene flow in the proximal regions. This reduction in gene flow is probably very difficult to detect with the set of chromosomes specific microsatellite makers available at present in the common shrew [12]. More makers with known subchromosomal localisation have to be developed.…”

Section: Discussionmentioning

confidence: 99%

Chromosome Synapsis and Recombination in Male Hybrids Between Two Chromosome Races of the Common Shrew (<em>Sorex araneus</em> L., Soricidae, Eulipotyphla)

Belonogova

Polyakov

Карамышева

et al. 2018

Preprint

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Abstract:Hybrid zones between chromosome races of the common shrew (Sorex araneus) provide exceptional models to study the potential role of chromosome rearrangements in the initial steps of speciation. The Novosibirsk and Tomsk races differ by a series of Robertsonian fusions with monobrachial homology. They form a narrow hybrid zone and generate hybrids with both simple (chain of three chromosomes) and complex (chain of eight or nine) synaptic configurations. Using immunolocalisation of the meiotic proteins, we examined chromosome pairing and recombination in males from the hybrid zone. Homozygotes and simple heterozygotes for Robertsonian fusions showed a low frequency of synaptic aberrations (< 10%). The carriers of complex synaptic configurations showed multiple pairing abnormalities, which might lead to reduced fertility. The recombination frequency in the proximal regions of most chromosomes of all karyotypes was much lower than in the other regions. The strong suppression of recombination in the pericentromeric regions and co-segregation of race specific chromosomes involved in the long chains would be expected to lead to linkage disequilibrium between genes located there. Genic differentiation, together with the high frequency of pairing aberrations in male carriers of the long chains, might contribute to maintenance of the narrow hybrid zone.

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CHROMOSOMAL REARRANGEMENTS DO NOT SEEM TO AFFECT THE GENE FLOW IN HYBRID ZONES BETWEEN KARYOTYPIC RACES OF THE COMMON SHREW (SOREX ARANEUS)

Cited by 63 publications

References 51 publications

Reduced recombination patterns in Robertsonian hybrids between chromosomal races of the house mouse: chiasma analyses

Reduced recombination patterns in Robertsonian hybrids between chromosomal races of the house mouse: chiasma analyses

Intra-species structuring in the common shrew Sorex araneus (Lipotyphla: Soricidae) in European Russia: morphometric variability could give evidence of limitation of interpopulation migration

Chromosome Synapsis and Recombination in Male Hybrids Between Two Chromosome Races of the Common Shrew (<em>Sorex araneus</em> L., Soricidae, Eulipotyphla)

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