Chromosomal rearrangements induced in mouse spermatogonia by 14.5-MeV neutrons

RBE and genetic susceptibility of mouse and rat spermatogonial stem cells to protons, heavy charged particles and 1.5MeV neutrons

“…It is important to mention that after X-or gamma irradiation the dose-response curves obtained are similar to those obtained with specific locus mutations (Batchelor et al, 1967;Russell, 1962;Searle and Phillips, 1967). The comparison between the mutation rates of neutron and gamma irradiation based on linear dose-effect dependence amounts to an RBE of 6.6, which is similar to values reported by other authors (Domshlak et al, 1970;Matsuda et al, 1987;Muramatsu et al, 1973;Searle et al, 1969;Valentin, 1975). The highest RBE was reported from Grahn et al (1983Grahn et al ( , 1984) especially for the low dose range 1-10 cGy.…”