Chromosome aberrations in lymphocytes of high-voltage laboratory cable splicers exposed to electromagnetic fields.

Skyberg, Knut; Hansteen, Inger-Lise; Vistnes, Arnt Inge

doi:10.5271/sjweh.1507

Cited by 44 publications

(29 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The maintenance electricians had mainly worked with 220-V alternating current, and they were known to have had frequent exposure to electric discharges, which have been proposed as a cause of chromosome aberrations (25,26). Awareness against electric shock has been much higher in the power plants, rectifiers, and potlines of the smelter, due to the higher voltages or much stronger currents.…”

Section: Cancers Of the Brain And Lymphatic And Hematopoietic Tissuementioning

confidence: 99%

Occupational exposure and cancer incidence among workers from an aluminum smelter in western Norway

Rønneberg¹,

Haldorsen²,

Romundstad³

et al. 1999

Scand J Work Environ Health

View full text Add to dashboard Cite

Occupational exposure and cancer incidence among workers from an aluminum smelter in western Norway by Rønneberg A, Haldorsen T, Romundstad P, Andersen AThe following articles refer to this text: 2008;34(6) Objectives This study investigated the associations between specific cancers and occupational exposure to polycyclic aromatic hydrocarbons (PAH), asbestos, electromagnetic fields, and heat in a cohort of workers from a Norwegian aluminum smelter. Methods Cancer incidence between 1953 and 1993 was observed for 2647 male short-term workers and 2 cohorts of men with at least 4 years' ernploylnent (2888 production workers and 373 maintenance workers). Standardized incidence ratios (SIR) were calculated from the national male cancer incidence, and associations with cumulative exposure were investigated by stratified analysis. Cumulative exposure in 15-year time windows was used as an alternative dose indicator. Results Investigation of the a priori hypotheses in the production cohort revealed a positive association between bladder cancer and PAH exposure 30 years or more before observation. The results also suggested an association between PAH and pancreatic cancer, although not statistically significant. No association was seen between exposure to PAH and cancers of the lungs or between magnetic field exposure and lymphatic and hematopoietic cancer. In the maintenance cohort there was a positive association between elnployment as an electrician and lymphatic and hematopoietic cancer and a statistically nonsignificant association between PAH and lung cancer. The short-term workers showed a statistically significant excess of lung cancer. C O~~~U S~O~S The results support previous findings of an association between exposure to PAH and bladder cancer.

show abstract

Section: Cancers Of the Brain And Lymphatic And Hematopoietic Tissuementioning

confidence: 99%

Occupational exposure and cancer incidence among workers from an aluminum smelter in western Norway

Rønneberg¹,

Haldorsen²,

Romundstad³

et al. 1999

Scand J Work Environ Health

View full text Add to dashboard Cite

show abstract

“…Some studies have been performed on samples taken from individuals professionally exposed. Increases in micronuclei frequencies and chromosomal aberrations have been observed in lymphocytes of photocopying machine workers (Iravathy Goud et al 2004), powerline operators and railwaymen (Nordenson et al 1984, 2001, Skyberg et al 1993, Valjus et al 1993.…”

Section: Introductionmentioning

confidence: 99%

Clastogenicity and aneuploidy in newborn and adult mice exposed to 50 Hz magnetic fields

Udroiu

Cristaldi

Ieradi

et al. 2006

International Journal of Radiation Biology

View full text Add to dashboard Cite

Purpose: To detect possible clastogenic and aneugenic properties of a 50 Hz, 650 mT magnetic field. Materials and methods: The micronucleus test with CREST (Calcinosis, Raynaud's phenomenon, Esophageal dismotility, Sclerodactility, Telangectasia) antibody staining was performed on liver and peripheral blood sampled from newborn mice exposed to an ELF (Extremely Low Frequency) magnetic field during the whole intra-uterine life (21 days), and on bone marrow and peripheral blood sampled from adult mice exposed to the same magnetic field for the same period. Results: Data obtained in newborn mice show a significant increase in micronuclei frequencies. In absolute terms, most of the induced micronuclei were CREST-negative (i.e., formed by a chromosome fragment). However, in relative terms, ELF exposure caused a two-fold increase in CREST-negative micronuclei and a four-fold increase in CREST-positive micronuclei (i.e., formed by a whole chromosome). No significant effect was recorded on exposed adults. Conclusions: These findings suggest the need for investigation of aneugenic properties of ELF magnetic fields in order to establish a possible relationship to carcinogenesis.

show abstract

“…Studies on wire production [Skyberg et al, 1993] support, to some extent, the hypothesis of an increased risk of genotoxic effects among high-voltage laboratory workers.…”

Section: Discussionmentioning

confidence: 97%

“…In electric wire production, alternating magnetic field levels at 50 Hz of 5-15 µT have been observed. Occasionally, the static and alternating magnetic fields are 500 µT (body) and 10,000 µT (hand) [Skyberg et al, 1993]. Magnetic field pulses in the control room have been measured to be about 20 µT.…”

Section: Methodsmentioning

confidence: 99%

Male proportion in offspring of parents exposed to strong static and extremely low-frequency electromagnetic fields in Norway

et al. 1997

View full text Add to dashboard Cite

Chromosome aberrations in lymphocytes of high-voltage laboratory cable splicers exposed to electromagnetic fields.

Cited by 44 publications

References 18 publications

Occupational exposure and cancer incidence among workers from an aluminum smelter in western Norway

Occupational exposure and cancer incidence among workers from an aluminum smelter in western Norway

Clastogenicity and aneuploidy in newborn and adult mice exposed to 50 Hz magnetic fields

Male proportion in offspring of parents exposed to strong static and extremely low-frequency electromagnetic fields in Norway

Contact Info

Product

Resources

About