Chronic actinic dermatitis

Roelandts, Rik

doi:10.1016/0190-9622(93)70034-q

Cited by 89 publications

(66 citation statements)

References 95 publications

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“…Patients with this condition have reduced MEDs and (photo)contact allergies are often noted. [32,33] We speculate that PhAD might be a preliminary stage of CAD that eventually results in this fierce persistent eczematous eruption. However, this possibility does not seem to exclude the existence of CAD at a young age.…”

Section: Discussionmentioning

confidence: 93%

Throwing a Light on Photosensitivity in Atopic Dermatitis

Berge

Weelden

Bruijnzeel-Koomen

et al. 2009

American Journal of Clinical Dermatology

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Section: Discussionmentioning

confidence: 93%

Throwing a Light on Photosensitivity in Atopic Dermatitis

Berge

Weelden

Bruijnzeel-Koomen

et al. 2009

American Journal of Clinical Dermatology

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“…Chronic actinic dermatitis includes numerous photodermatoses such as photosensitive eczema, photosensitivity dermatitis, persistent light reaction, and actinic reticuloid. 144 As indicated in Table IV, strong J AM ACAD DERMATOL VOLUME 55,NUMBER 3 data support the use of azathioprine in the treatment of chronic actinic dermatitis. 128,[145][146][147][148][149][150] Some consider it the first choice for long-term immunosuppression of this condition.…”

Section: Photodermatosesmentioning

confidence: 83%

Azathioprine in dermatology: The past, the present, and the future

Patel

Swerlick

McCall

2006

Journal of the American Academy of Dermatology

160

136

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“…80–82 Chronic actinic dermatitis patients may or may not have a positive photoallergic response, but even in those who do, the dermatitis persists despite removal of the substance causing the problem. Many of these patients initially have a photosensitivity to UVB, but this frequently extends to the UVA and even visible light.…”

Section: Photoimmunological Diseasesmentioning

confidence: 99%

“…82–84 Another characteristic suggesting that chronic actinic dermatitis is immunologically-mediated is that the disease responds to immunosuppressive agents. 80, 82 …”

Section: Photoimmunological Diseasesmentioning

confidence: 99%

Photoimmunology

Elmets

Cala

2014

Dermatologic Clinics

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SYNOPSIS The discipline that investigates the biological effects of ultraviolet radiation on the immune system is called photoimmunology. Photoimmunology evolved from an interest in understanding the role of the immune system in skin cancer development, and why immunosuppressed organ transplant recipients are at greatly increased risk for cutaneous neoplasms. Ultraviolet radiation-induced damage DNA modifies the antigen presenting function of cutaneous dendritic cells, biases the immune response towards the generation of regulatory T-cells and stimulates epidermal keratinocyte production of immunosuppressive cytokines. In addition to contributing to an understanding of the pathogenesis of non-melanoma skin cancer, the knowledge acquired about the immunological effects of ultraviolet radiation exposure has provided an understanding of its role in the pathogenesis of other photodermatologic diseases such as polymorphous light eruption, chronic actinic dermatitis and cutaneous lupus erythematosus. This information has also been helpful in developing more effective and safer phototherapeutic devices for the treatment of a variety of cutaneous diseases.

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Chronic actinic dermatitis

Cited by 89 publications

References 95 publications

Throwing a Light on Photosensitivity in Atopic Dermatitis

Throwing a Light on Photosensitivity in Atopic Dermatitis

Azathioprine in dermatology: The past, the present, and the future

Photoimmunology

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