Chronic aortic counterpulsation with latissimus dorsi in heart failure: clinical follow-up

This study was designed to compare the effects of juxtaaortic balloon counterpulsation (JABC), performed in ascending aorta and the aortic arch, with those yielded by intraaortic balloon counterpulsation (IABC) in descending aorta, in experimental animals during induced cardiac failure.JABC was achieved with a manufactured Dacron prosthesis and a balloon pump placed between the prosthesis and the wrapped aorta.JABC resulted in a significant increase of cardiac output (from 2.33 ؎ 0.82 to 2.61 ؎ 1.12 L/min, p < 0.05), cardiac index (from 0.071 ؎ 0.025 to 0.080 ؎ 0.033 L/min/kg, p < 0.05) and diastolic pressure augmentation evaluated through diastolic and systolic areas beneath the aortic pressure curve (DABAC/SABAC) index (from 0.94 ؎ 0.21 to 1.10 ؎ 0.33, p < 0.01). End diastolic aortic pressure showed a significant decrease with JABC (from 31.90 ؎ 7.09 to 27.83 ؎ 9.72 mm Hg, p < 0.05). A close association between percentage of DABAC/SABAC increases obtained with IABC and JABC was observed (r 2 ‫؍‬ 0.67; p < 0.001).Counterpulsation obtained by a juxtaaortic catheter placed in the arch and the ascending wrapped aorta results in an effective hemodynamic improvement comparable with that achieved by an intraaortic catheter in open chest sheep.

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“…14,15 The material used in this study (Dacron) is a biocompatible and has been extensively used in replacing human vessels.…”

Section: Discussionmentioning

confidence: 99%

Juxtaaortic Counterpulsation: Comparison with Intraaortic Counterpulsation in an Animal Model of Acute Heart Failure

et al. 2004

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“…In this series, we used an animal model of pharmacologically induced acute cardiac dysfunction which has been previously reported (12). Aortic counterpulsation is well tolerated for long periods of time in patients with heart failure, such as after dynamic aortomyoplasty procedure (13), and Dacron prostheses are well tolerated in the ascending aorta, having been used to wrap the ascending aorta in patients suffering from arterial aneurysm.…”

Section: Discussionmentioning

confidence: 99%

A New Approach to Assist Postoperative Heart Failure in an Animal Model: Juxta‐Aortic Counterpulsation

et al. 2002

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Aortic counterpulsation is a useful technique frequently used in postcardiotomy heart failure. An acute heart failure model in open chest sheep was chosen to evaluate hemodynamic improvement with a counterpulsation balloon pump in juxta‐aortic position. This was achieved with a manufactured Dacron prosthesis and a balloon pump placed between the prosthesis and the aorta. Juxta‐aortic balloon pump counterpulsation in acute experimental heart failure resulted in a significant improvement of hemodynamic parameters: increase of cardiac output (from 0.86 ± 0.04 to 1.29 ± 0.09 L/min, p < 0.05) and cardiac index (from 0.03 ± 0.01 to 0.04 ± 0.01 L/min per kg, p < 0.05), and decrease of systemic vascular resistance (from 89.76 ± 6.69 to 66.56 ± 6.02 mm Hg/L per min, p < 0.05). The extent of aortic diastolic pressure change evaluated through the diastolic and systolic areas beneath the aortic pressure curve (DABAC/SABAC) index before cardiac failure induction showed a significant increase compared with unassisted values (from 0.81 ± 0.10 to 1.12 ± 0.09, p < 0.05). Assisted values of DABAC/SABAC index after heart failure induction also showed a significant increase compared with unassisted values (from 0.78 ± 0.21 to 1.17 ± 0.38, p < 0.05). Treatment of experimental acute heart failure by juxta‐aortic balloon pump counterpulsation allows an effective hemodynamic improvement in open chest sheep.

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“…Evaluating data from 264 patients of 7 publications [31], [35], [40], [96], [118], [136], [138], the pre-operative hospitalization rate was 2.79 ± 0.83 days/year. The post-operative hospitalizationrate of DCMP patients was significantly decreased with 0.48 ± 0.23 days/year ( Figure 8).…”

Section: Hospitalization Ratementioning

confidence: 99%

Autologous Muscular Treatment Options for Endstage Heart Failure — A Critical Appraisal of the Dynamic Cardiomyoplasty (DCMP) vs. a New Concept of a Closed-Loop Controlled DCMP (CLC-DCMP)

Guldner¹,

Klapproth²,

Sievers³

2013

Regenerative Medicine and Tissue Engineering

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Chronic aortic counterpulsation with latissimus dorsi in heart failure: clinical follow-up

Cited by 9 publications

References 16 publications

Juxtaaortic Counterpulsation: Comparison with Intraaortic Counterpulsation in an Animal Model of Acute Heart Failure

Juxtaaortic Counterpulsation: Comparison with Intraaortic Counterpulsation in an Animal Model of Acute Heart Failure

A New Approach to Assist Postoperative Heart Failure in an Animal Model: Juxta‐Aortic Counterpulsation

Autologous Muscular Treatment Options for Endstage Heart Failure — A Critical Appraisal of the Dynamic Cardiomyoplasty (DCMP) vs. a New Concept of a Closed-Loop Controlled DCMP (CLC-DCMP)

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