“…55,56 Reported risk factors for CKD after HCT are sex, age, previous renal impairment, type of HCT (autologous vs allogeneic), TBI exposure, acute or chronic GVHD, development of VOD, post transplant exposure to nephrotoxic medications (aminoglycosides, amphotericin B and vancomycin), post transplant hypertension, post-HCT AKI and long-term use of CYA; the most common causes of CKD following HCT are chronic CYA nephrotoxicity and thrombotic microangiopathy. 53,[57][58][59][60][61][62][63] Chronic CYA therapy can cause nephrotoxicity similar to that seen in other settings, such as solid organ transplantation. Long-term complications are, however, unusual in HCT because CYA is given in full doses to stable patients for only several months.…”