Chronic kidney disease, inflammation, and cardiovascular disease risk in rheumatoid arthritis

Kochi, Masako; Kohagura, Kentaro; Shiohira, Yoshiki; Iseki, Kunitoshi; Ohya, Yusuke

doi:10.1016/j.jjcc.2017.08.008

Cited by 37 publications

(30 citation statements)

References 44 publications

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“…Недавние исследования показали, что при РА ХБП ассоциирована с высоким риском возникновения ССЗ, независимо от традиционных сердечно-сосудистых ФР [41,42]. H.Y.…”

Section: хбп и риск развития ссзunclassified

“…В другом ретроспективном исследовании M. Kochi и соавт. [41] продемонстрировали связь между повышением сывороточного уровня СРБ и развитием ХБП. К тому же воспаление, характеризующееся высоким уровнем СРБ, было связано с повышенным риском ССЗ, и сопутствующая ХБП еще больше увеличивала этот риск, хотя изолированное влияние почечной недостаточности на риск развития кардиоваскулярной патологии было незначительным.…”

Section: хбп и риск развития ссзunclassified

“…Мы не встретили публикаций, посвященных изучению КРС у больных РА. Имеются малочисленные когортные исследования распространенности ХБП и взаимосвязи почечной патологии с ССЗ и сердечно-сосудистыми ФР у данных пациентов [36,41,42,52]. Летальность, обусловленная сердечно-сосудистой патологией, по-прежнему является доминирующей в структуре смертности больных РА.…”

Section: крс и раunclassified

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Cardiorenal syndrome in patients with rheumatoid arthritis

Мутовина

Zagrebneva

Галушко³

et al. 2019

Sovremennaâ revmatologiâ

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В современном понимании кардиоренальный синдром (КРС)-патологические взаимообусловленные состояния с вовлечением сердца и почек, развивающиеся вследствие острой или хронической дисфункции одного из органов с последующей острой или хронической дисфункцией другого [1]. В 2008 г. инициативной группой ADQI (Acute Dialysis Quality Initiative) была утверждена классификация, которая выделяет пять типов КРС в зависимости от патофизиологи-ческих и временных рамок развития кардиальной и почечной недостаточности (табл. 1) [2]. Типы КРС КРС 1-го типа-тяжелое нарушение функции сердца (кардиогенный шок, острая декомпенсация хронической сердечной недостаточности, ХСН), которое приводит к острому повреждению почек (ОПП). Развитие ОПП при

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Section: хбп и риск развития ссзunclassified

Section: крс и раunclassified

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Cardiorenal syndrome in patients with rheumatoid arthritis

Мутовина

Zagrebneva

Галушко³

et al. 2019

Sovremennaâ revmatologiâ

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“…This chapter will present an uptodate findings relating to chronic systemic inflammation and CKD, with emphasis on gut dysmicrobism involvement and whether intervention on gut microbiota could be proven beneficial for the outcome of this fatal disease. disease (ESRD), which shifts the perception of inflammation as no longer a new, but rather a traditional risk factor for CKD morbidity and mortality [14,21]. A challenging theory regarding the direct effect of inflammation on the progression of both CKD and cardiovascular disease came out with the assumption of association between markers of inflammation, changes in GFR and nutrition habits in elderly individuals.…”

Section: Introductionmentioning

confidence: 99%

Inflammation and Chronic Kidney Disease: Current Approaches and Recent Advances

Mihai¹,

Codrici²,

Popescu³

et al. 2018

Chronic Kidney Disease - From Pathophysiology to Clinical Improvements

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Despite being a "silent epidemic" disease, chronic kidney disease (CKD) is considered one of the major causes of mortality, together with its main complication, the cardiovascular disease, which contributes to the poor prognosis of these patients. Inflammation has been recognized as an essential part of CKD and is closely linked to cardiovascular complications. The identification of novel biomarkers using omics technologies is rapidly advancing and could improve the early detection in renal diseases. Omics approaches, including proteomics, could provide novel insights into disease mechanisms, identifying at the same time accurate inflammatory biomarker panels with an essential role in disease monitoring and follow-up. Recent advances highlight the gut microbiota as an important source of inflammation in kidney diseases. An increasing body of evidence reveals the cross talk between microbiota and host in CKD; in addition, gut dysbiosis may represent an underappreciated cause of inflammation and subsequently could lead to malnutrition, accelerated cardiovascular disease and CKD progression. This chapter discusses the relationship between inflammation and CKD and highlights the novel approaches regarding microbiota involvement in CKD pathology, as well as their potential to facilitate improving the quality of life.

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“…Complications of Rheumatoid arthritis increases the risk of developing, osteoporosis, rheumatoid nodules, dry eyes and mouth, infections, abnormal body composition, carpal tunnel syndrome, CVD 5,6,8,9,10 Considering all the above factors we set the following as the main objectives of our study to measure the outcomes in the biological, emotional and psychosocial factors measured as QOL (quality of life) as assessed by questionnaire among the respondents, to evaluate unreported and undiagnosed prevalent RA cases, to assess awareness about the disease conditions and knowledge about the impact of physical illness on mental health among our respondents and to provide necessary counseling to each individual respondent about the importance of knowledge over the disease RA, disease monitoring, and self-assessment of QOL.…”

Section: Introductionmentioning

confidence: 99%

Appraisal of the Impact of Rheumatoid Arthritis on the Quality of Life Using Sf-36: A Cross Sectional Study

Thadiboina¹,

Vadivel²,

Babu³

2018

J. Pharm. Sci. Innov.

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Rheumatoid arthritis is a progressive systemic autoimmune disease. The untreated RA can lead to joint damage and loss of function. The major complications include. The main aim and objectives of our work are to evaluate the respondent's quality of life using a standard questionnaire, to assess the knowledge over the disease condition, to report the number of unreported cases of rheumatoid arthritis, to educate and counsel individual respondent. A cross-sectional study was conducted in a population of 1650 and 38 respondents with rheumatoid arthritis positive were obtained. Among the 38 respondents, we have noticed 7 unreported cases of rheumatoid arthritis. It was confirmed by the algorithm of the World health organization. All the 38 respondents were made to answer the 36 questions as per the protocol and the data were recorded. Later the score was calculated using a software-online SF-36 calculator. In our study it was found that females were suffering more than males and experiencing a low quality of life, whereas the extra-articular manifestations were more reported in males, and the respondents on regular medication were doing better and 7 respondents were unaware of having rheumatoid arthritis.32 respondents were unaware of the concept that the physical illness affects the mental health. Finally, all the patients were counseled as per the objectives of our study. Thus our study brings to notice about the burden of rheumatoid arthritis in India, need to provide the necessary knowledge about the disease state and the self-assessment of the quality of life.

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Chronic kidney disease, inflammation, and cardiovascular disease risk in rheumatoid arthritis

Abstract: The coexistence of CKD and inflammation was associated with a higher risk of CVD than either condition alone in RA patients. Inflammation might increase the risk of CVD especially in patients with CKD.

Cited by 37 publications

References 44 publications

Cardiorenal syndrome in patients with rheumatoid arthritis

Cardiorenal syndrome in patients with rheumatoid arthritis

Inflammation and Chronic Kidney Disease: Current Approaches and Recent Advances

Appraisal of the Impact of Rheumatoid Arthritis on the Quality of Life Using Sf-36: A Cross Sectional Study

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