Chronic Obstructive Pulmonar Disease Mortality. SEPAR COPD-Smoking Year

Granda‐Orive, José Ignacio de; Solano-Reina, Segismundo

doi:10.1016/j.arbr.2016.06.017

Archivos de Bronconeumología (English Edition)

2016

DOI: 10.1016/j.arbr.2016.06.017

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Chronic Obstructive Pulmonar Disease Mortality. SEPAR COPD-Smoking Year

José Ignacio de Granda‐Orive

Segismundo Solano-Reina

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Cited by 3 publications

References 12 publications

(10 reference statements)

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Readmission Due to Exacerbation of COPD: Associated Factors

Lajas

Gutiérrez‐González

Parrado

et al. 2018

Lung

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Chronic obstructive pulmonary disease patients with HFR are more frequently male, older, have worse dyspnea, lower lung function, belong more frequent to exacerbator emphysema phenotype, and more frequently diabetics. The variables that continued to be independent predictors of HFR in the multivariate analysis were sex, phenotype, occurrence of complications during admission, destabilized heart failure, and length of hospital stay.

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Readmission Due to Exacerbation of COPD: Associated Factors

Lajas

Gutiérrez‐González

Parrado

et al. 2018

Lung

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Ethnic Inequalities in COPD Outcomes: a Register-Based Study in Copenhagen, Denmark

Cantarero-Arévalo

Frølich

et al. 2016

J. Racial and Ethnic Health Disparities

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The aim of this study was to investigate the differences in age at diagnosis and survival time after diagnosis between Chronic Obstructive Pulmonary Disease (COPD) patients with native Danish and other ethnic backgrounds. Individuals diagnosed with COPD in a hospital setting in Copenhagen in the period 2003-2007 were identified from annual hospital contact records. The cohort was restricted to COPD patients older than 35 years old at diagnosis. Follow-up was available until the end of 2010. ANOVA was conducted to test if mean age at diagnosis differed between the patient groups with different ethnicity. Kaplan-Meier estimator was used to estimate survival time after diagnosis. Cox proportional hazards models were conducted to calculate hazards of death according to ethnicity. A total of 2845 COPD patients were included; 131 (4.6%) were with non-Western ethnic minority backgrounds. Patients with non-Western ethnic backgrounds were diagnosed at a younger age and had a better survival probability compared to ethnic Danish patients; hazard ratio HR (95% CI) for death during follow-up in non-Western vs. ethnic Danish patients was 0.33 (0.18-0.62). Our study showed marked differences in age at diagnosis and survival time after diagnosis between the COPD patients with different ethnic backgrounds residing in Copenhagen. Further studies are needed to find out the reasons for younger age of COPD diagnosis in non-Western minorities and for shorter survival time after diagnosis in ethnic Danish COPD patients.

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Hospital admissions and mortality in patients with COPD exacerbations and vertebral body compression fractures

Pascual-Guardia¹,

Badenes-Bonet²,

Martín-Ontiyuelo³

et al. 2017

COPD

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BackgroundVertebral compression fractures (VCF) are common in COPD patients, with osteoporosis being the main cause. The clinical impact of VCF derives mostly from both pain and chest deformity, which may lead to ventilatory and physical activity limitations. Surprisingly, the consequences of VCF on the quality outcomes of hospital care are poorly known.ObjectiveTo assess these indicators in patients hospitalized due to a COPD exacerbation (ECOPD) who also have VCF.MethodsClinical characteristics and quality care indicators were assessed in two one-year periods, one retrospective (exploratory) and one prospective (validation), in all consecutive patients hospitalized for ECOPD. Diagnosis of VCF was based on the reduction of >20% height of the vertebral body evaluated in standard lateral chest X-ray (three independent observers).ResultsFrom the 248 patients admitted during the exploratory phase, a third had at least one VCF. Underdiagnosis rate was 97.6%, and patients with VCF had more admissions (normalized for survival), longer hospital stays, and higher mortality than patients without (4 [25th–75th percentiles, 2–8] vs 3 [1–6] admissions, P<0.01; 12 [6–30] vs 9 [6–18] days, P<0.05; and 50 vs 32.1% deaths, P<0.01, respectively). The risk of dying in the two following years was also higher in VCF patients (odds ratio: 2.11 [1.2–3.6], P<0.01). The validation cohort consisted of 250 patients who showed very similar results. The logistic regression analysis indicated that both VCF and age were factors independently associated with mortality.ConclusionAlthough VCF is frequently underdiagnosed in patients hospitalized for ECOPD, it is strongly associated with a worse prognosis and quality care outcomes.

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Chronic Obstructive Pulmonar Disease Mortality. SEPAR COPD-Smoking Year

Cited by 3 publications

References 12 publications

Readmission Due to Exacerbation of COPD: Associated Factors

Readmission Due to Exacerbation of COPD: Associated Factors

Ethnic Inequalities in COPD Outcomes: a Register-Based Study in Copenhagen, Denmark

Hospital admissions and mortality in patients with COPD exacerbations and vertebral body compression fractures

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