Chronic Pancreatitis in the Elderly in Japan

Kamisawa, Terumi; Yoshiike, Masami; Egawa, Naoto; Nakajima, Hitoshi; Tsuruta, Kouji; Okamoto, Akira; Nakamura, Teruo

doi:10.1159/000078433

Cited by 35 publications

(11 citation statements)

References 14 publications

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“…These clinicopathological characteristics were reportedly common in the patients with AIP (10)(11)(12)(13) (5,6,14). The present case report clearly shows that the condition was systemic and that pancreatitis was not an essential feature.…”

Section: Csupporting

confidence: 59%

Lymphoplasmacytic Infiltration of Multiple Organs with Immunoreactivity for IgG4: IgG4related Systemic Disease

et al. 2006

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Section: Csupporting

confidence: 59%

Lymphoplasmacytic Infiltration of Multiple Organs with Immunoreactivity for IgG4: IgG4related Systemic Disease

et al. 2006

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“…With the declining of endocrine function in geriatrics, DM and steatorrhea were more common as the initial symptom of CP, while abdominal pain was more common in young patients. Elderly CP patients were reported with less severe pain, which lead to more patients without pain in the geriatric group, while RP and recurrent acute pancreatitis plus RP were much less than in the control group.…”

Section: Discussionmentioning

confidence: 90%

Extracorporeal shock wave lithotripsy is safe and effective for geriatric patients with chronic pancreatitis

Liang

Liu

Wang

et al. 2019

J of Gastro and Hepatol

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Background and Aim Pancreatic extracorporeal shock wave lithotripsy (P‐ESWL) is a first‐line treatment for chronic pancreatitis (CP) patients with pancreatic stones. However, the performance of P‐EWSL in geriatric patients remains unclear. We aimed to evaluate the safety and efficacy of P‐ESWL for them. Methods This prospective study was conducted in painful CP patients who underwent P‐ESWL. Patients aged over 65 years were included in geriatric group; patients aged under 65 years were assigned to control group. For the long‐term follow‐up investigation, geriatric patients were matched with patients from the control group in a 1:1 ratio. Primary outcomes were complications of P‐ESWL and pain relief. Secondary outcomes included stone clearance, physical and mental health, quality of life score, changes in exocrine and endocrine pancreatic function, and survival. Results From March 2011 to March 2016, P‐ESWL was performed in 1404 patients (72 in the geriatric group and 1332 in the control group). No significant differences were observed in complications of P‐ESWL between the two groups (P = 0.364). Among the 67 (67/72, 93.1%) geriatric patients who underwent follow up for 4.02 years, complete pain relief was achieved in 53 patients, which was not significantly different from that of matched controls (54/70; P = 0.920). The death in the geriatrics was significantly higher (P = 0.007), but none of them were correlated with P‐ESWL. Conclusions P‐ESWL is safe and effective for geriatric CP patients with pancreatic stones. It can promote significant pain relief and stone clearance and improve quality of life and mental and physical health.

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“…Moreover, the cumulative risk of pancreatic cancer increased distinctly, and 10 and 20 years after a diagnosis of CP, the risks were found to be 1.8 and 4%, respectively, in a multicenter study conducted by Lowenfels et al[ 24]. The incidence of associated pancreatic cancer was found to be 1.6% in a recent Japanese study[ 28], and the overall incidence of pancreatic cancer in our study was 3.1%, which is similar to several Western studies that reported a higher incidence of pancreatic cancer in CP [20, 26, 27]. Smoking is the most well-established risk factor of pancreatic cancer, and this risk appears to be independent of sex, country, or type of pancreatitis[ 25].…”

Section: Discussionmentioning

confidence: 99%

Clinical Features of Chronic Pancreatitis in Korea: A Multicenter Nationwide Study

Ryu¹,

Lee²,

Kim³

et al. 2005

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Background/Aims: No reliable nationwide clinical data about chronic pancreatitis (CP) was available in Korea. The etiology and clinical features of CP were investigated using a multicenter nationwide study. Methods: 814 cases of CP were enrolled retrospectively over the past 4 years at 13 hospitals. The following data were obtained from all patients: etiology, symptoms, complications, and surgery. Result: Alcohol (64.3%) was the major cause of CP and idiopathic CP (20.8%) was the second most common form. Mean patient age was 50.6 years and the male:female ratio was 6:1 (24:1 for alcoholic CP vs. 2:1 in idiopathic CP, p < 0.001). Diabetes (31.6%), pseudocysts (28.4%), biliary stricture (13.9%), and pancreatic ascites (6.6%) were the main complications. Of these, diabetes (35 vs. 26%) and pseudocyst (33.7 vs. 21.9%) were more frequent in alcoholic than in idiopathic CP. Pancreatic cancer developed in 25 patients (3.1%) during follow-up and their mean age was 59.1 years. Conclusions: In Korea, alcohol is the most common etiology of CP. Moreover, diabetes and pseudocysts are frequent complications, especially in alcoholic CP, and pancreatic cancer development is not infrequent.

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Chronic Pancreatitis in the Elderly in Japan

Cited by 35 publications

References 14 publications

Lymphoplasmacytic Infiltration of Multiple Organs with Immunoreactivity for IgG4: IgG4related Systemic Disease

Lymphoplasmacytic Infiltration of Multiple Organs with Immunoreactivity for IgG4: IgG4related Systemic Disease

Extracorporeal shock wave lithotripsy is safe and effective for geriatric patients with chronic pancreatitis

Clinical Features of Chronic Pancreatitis in Korea: A Multicenter Nationwide Study

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