2013
DOI: 10.2500/ajra.2013.27.3952
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Chronic Rhinosinusitis Confers an Increased Risk of Acute Myocardial Infarction

Abstract: Patients with CRS were at higher risk for AMI occurrence in the 6-year follow-up.

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Cited by 26 publications
(36 citation statements)
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“…Recent epidemiological studies have identified an increased risk of subsequent stroke and acute myocardial infarction in patients with CRS131415. In previous studies on CRS patients, the HRs of stroke, ischemic stroke, and acute myocardial infarction were 1.34 (95% CI = 1.04–1.74)13, 1.34 (95% CI = 1.18–1.53), and 1.48 (95% CI = 1.32–1.67)15, respectively, after adjustment for potential confounding factors.…”
Section: Discussionmentioning
confidence: 99%
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“…Recent epidemiological studies have identified an increased risk of subsequent stroke and acute myocardial infarction in patients with CRS131415. In previous studies on CRS patients, the HRs of stroke, ischemic stroke, and acute myocardial infarction were 1.34 (95% CI = 1.04–1.74)13, 1.34 (95% CI = 1.18–1.53), and 1.48 (95% CI = 1.32–1.67)15, respectively, after adjustment for potential confounding factors.…”
Section: Discussionmentioning
confidence: 99%
“…CRS was identified in this study by the claims records showing a primary diagnosis of CRS designated with the use of the International Classification of Diseases, Ninth Revision (ICD-9) codes CRS1517 (ICD-9 codes: 473, 473.0, 473.1, 473.2, 473.3, 473.8, and 473.9) from 1996 to 2007. Date of diagnosis was set as the index date.…”
Section: Methodsmentioning
confidence: 99%
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“…None of the conditions evaluated (hypertension, heart failure) nor risk factors for these conditions (diabetes, obesity) were associated with incident CRS. Recently a few population-based case-control studies published using a national insurance database in Taiwan have demonstrated that patients with CRS are at a higher risk for cerebrovascular diseases (53), and myocardial infarctions (54, 55), post-CRS diagnosis. In these studies, CRS patients were more likely to have a diagnosis of ischemic stroke during a 5-year follow-up period (OR: 1.3 95% CI: 1.2–1.5) and myocardial infarction during a 3-year follow-up period (OR: 1.8; 95% CI: 1.4–2.4) when compared to a control group consisting of patients matched on sex, age, and urbanization level.…”
Section: Associations With Heart and Vascular Diseasementioning
confidence: 99%
“…Ogretmenoglu and his group showed that even light bilateral nasal packing has a strong influence on arterial blood gases and heart rate 20 .The connection between particular types of nasal septal deformities (NSD) and minimal cross-sectional area of the nasal cavity and body surface area has been confirmed ten years ago 21 . Most recently, the ostensible connection between chronic rhinosinusitis (CRS) and acute myocardial infarction has been proven 22 . Focal accumulation of fluids containing proinflammatory cytokines and altered activation of the coagulation system in the paranasal sinuses has been reported in CRS patients 23,24 .…”
Section: Introductionmentioning
confidence: 99%