Chronic Vomiting in Cats: Etiology and Diagnostic Testing

Hauck, Shannon Ryan; Gisselman, Kelly; Cordner, Amy; Nicholson, Angela Gasser

doi:10.5326/jaaha-ms-6290

Cited by 7 publications

(5 citation statements)

References 29 publications

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“…Clinically, always in accordance with previous reports [15], patients presented mainly vomiting and diarrhea, followed by hematochezia and lastly presence of mucus in feces and weight loss. Regarding the only cat that presented anemia, it could be due to chronic inflammation or chronic GI bleeding [2,14], as no other cause was found during the work-up and follow-up.…”

Section: Resultssupporting

confidence: 90%

Immunohistochemical Findings in Idiopathic Inflammatory Bowel Disease in Nine Cats

Ricart

Feijóo

Rossi

et al. 2020

BioMed Research International

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Inflammatory bowel disease is a term referring to a clinical condition characterized by recurrent/persistent gastrointestinal signs, which cannot be diagnosed only through histological findings, being an elimination diagnosis and needing therefore the previous exclusion of all other possible causes of gastrointestinal signs. The aim of the present study was to compare the expression of different cytokines on endoscopic biopsy samples of the small and large intestine of cats suffering from inflammatory bowel disease and healthy controls, by immunohistochemistry evaluation. Nine cats referred for chronic gastrointestinal signs to the Gastroenterology Service, Teaching Hospital, Faculty of Veterinary Sciences, University of Buenos Aires, were included. After being administered with antiparasitic drugs and after running complete laboratory exams, abdominal ultrasonography, etc., upper and lower gastrointestinal endoscopy with biopsy samplings for histopathology and immunohistochemistry was then performed. Controls were represented by archived samples from healthy cats (University of Camerino, Italy, Veterinary Pathology Unit Archive). On biopsy samples, the immunohistochemistry expression of the following antibodies was evaluated: TGF-β, CD3+, FoxP3+, TNF-α, IL-1β, IL-10, IL-12, and Th-17+. Statistic analysis was performed with the nonparametric Mann-Whitney test and with Spearman test, considering significant p<0.05. TNF-α, IL-1β, IL-12, and CD3+ were significantly differently expressed between cats suffering from inflammatory bowel disease and controls, while no differences were found regarding TGF-β, IL-10, and FOXP3. A positive correlation was also found between proinflammatory cytokines and proinflammatory cytokines plus lymphocytes that were at the same time related to IL-10 and TGF-β. On the other hand, a negative correlation was found between proinflammatory and regulatory cytokines. Our results suggest an imbalance in the immune response which may play a role in the etiopathogenesis of feline inflammatory bowel disease.

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Section: Resultssupporting

confidence: 90%

Immunohistochemical Findings in Idiopathic Inflammatory Bowel Disease in Nine Cats

Ricart

Feijóo

Rossi

et al. 2020

BioMed Research International

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“…It may also be a clinical sign of inflammatory bowel disease (IBD) or low-grade lymphoma [ 61 ]. Vomiting is also extremely common in cats [ 62 ] and may be caused by food intolerance, inflammatory bowel disease, liver disease, pancreatitis, hyperthyroidism, and uremia [ 63 , 64 , 65 ]. Historically, constipation in cats has been tied to dehydration and is associated with chronic kidney disease (CKD), diabetes mellitus and hyperthyroidism [ 66 ].…”

Section: Discussionmentioning

confidence: 99%

Microbiome Responses to Fecal Microbiota Transplantation in Cats with Chronic Digestive Issues

Rojas,

Entrolezo,

Jarett

et al. 2023

Veterinary Sciences

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There is growing interest in the application of fecal microbiota transplants (FMTs) in small animal medicine, but there are few published studies that have tested their effects in the domestic cat (Felis catus). Here we use 16S rRNA gene sequencing to examine fecal microbiome changes in 46 domestic cats with chronic digestive issues that received FMTs using lyophilized stool that was delivered in oral capsules. Fecal samples were collected from FMT recipients before and two weeks after the end of the full course of 50 capsules, as well as from their stool donors (N = 10), and other healthy cats (N = 113). The fecal microbiomes of FMT recipients varied with host clinical signs and dry kibble consumption, and shifts in the relative abundances of Clostridium, Collinsella, Megamonas, Desulfovibrio and Escherichia were observed after FMT. Overall, donors shared 13% of their bacterial amplicon sequence variants (ASVs) with FMT recipients and the most commonly shared ASVs were classified as Prevotella 9, Peptoclostridium, Bacteroides, and Collinsella. Lastly, the fecal microbiomes of cats with diarrhea became more similar to the microbiomes of age-matched and diet-matched healthy cats compared to cats with constipation. Overall, our results suggest that microbiome responses to FMT may be modulated by the FMT recipient’s initial presenting clinical signs, diet, and their donor’s microbiome.

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“…A êmese é definida pela ejeção do conteúdo estomacal, de forma parcial ou total, e está conectado à diversas patologias como causa base para a queixa. O vômito pode apresentar-se de forma aguda ou crônica, estabelecida pelo tempo de evolução/regressão do sintoma e pela responsividade da terapêutica de suporte (HAUCK, 2016).…”

Section: Resultsunclassified

Potencial dos extratos vegetais como alternativa terapêutica isolada ou em associação sinérgica com fármacos dentro da Clínica de Felinos

Lucena¹,

Lima²

2022

Clínica Veterinária: Conhecimentos Práticos E Teóricos Em Torno Da Medicina Veterinária

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Chronic Vomiting in Cats: Etiology and Diagnostic Testing

Cited by 7 publications

References 29 publications

Immunohistochemical Findings in Idiopathic Inflammatory Bowel Disease in Nine Cats

Immunohistochemical Findings in Idiopathic Inflammatory Bowel Disease in Nine Cats

Microbiome Responses to Fecal Microbiota Transplantation in Cats with Chronic Digestive Issues

Potencial dos extratos vegetais como alternativa terapêutica isolada ou em associação sinérgica com fármacos dentro da Clínica de Felinos

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