Chylothorax and Nephrotic Syndrome

Chylous Ascites in an Adult Patient with Nephrotic Syndrome due to Membranous Nephropathy

“…The mean ratio of triglyceride to cholesterol values in these patients was 11.0 (7.2-15.9), suggesting that a ratio of Kato/Kohno/Ohtake/Takita/Hirshida 1 7.0 seems to be a good indicator for the diagnosis of chylous ascites. In our patient, the ascitic triglyceride/cholesterol ratio was increased to 10.0, a value compatible with the previous patients [2][3][4][5]. In contrast, a low triglyceride level of !…”

“…To our knowledge, except for the initial description [1], the complication of chyle has been reported in only 4 cases with adult nephrotic syndrome [2][3][4][5]. The characteristics of ascitic chyle are always associated with elevated triglyceride levels from 90 to 529 mg/dl and low cholesterol levels from 10 to 62 mg/dl [2][3][4][5][6].…”

Superior vena cava thrombosis and chylothorax: relationship in pediatric nephrotic syndrome

“…The origin of chylothorax in nephrotic syndrome is usually explained by transdiaphragmatic flow of chylous ascites through variably sized defects in the diaphragm [1,2]. We describe a patient with uncontrolled nephrotic syndrome who presented with chylothorax which did not originate from the abdomen.…”

An Unusual Complication of Nephrotic Syndrome: Chylothorax Treated with Hemodialysis

“…In the case reported here, the appearance of radionucleotide tracer in the pleural space after intraperitoneal injection confirmed that the cause of chylothorax was the flow of fluid across the diaphragm rather than diaphragmatic lymphatics. To our knowledge, this is the third reported case of chylothorax from chylous ascites in a nephrotic patient [2,3]. Interestingly, chylothorax in these three cases was identified exclusively in adults and presented only in the right hemithorax.…”

“…The nephrotic syndrome is known to be associated with chylous ascites [2,3]. In one early series involving nephrotic patients with hydroperitoneum, chylous ascites was documented in 52% of cases [4].…”