CIBERSAM: Ten years of collaborative translational research in mental disorders

Salagre, Estela; Arango, Celso; Artigas, Francesc; Ayuso-Mateos, José Luís; Bernardo, Miquel; Castro‐Fornieles, Josefina; Bobes, Julio; Desco, Manuel; Fañanás, Lourdes; González‐Pinto, Ana; Haro, Josep María; Leza, Juan C.; McKenna, Peter; Meana, J.J.; Menchón, José M.; Micó, Juan Antonio; Palomo, Tomás; Pazos, Ángel; Pérez, Ví­ctor; Sáiz-Ruiz, Jerónimo; Sanjuán, Julio; Tabarés‐Seisdedos, Rafael; Crespo‐Facorro, Benedicto; Casas, Miquel; Vilella, Elisabet; Palao, Diego; Olivares, José; Rodríguez‐Jiménez, Roberto; Vieta, Eduard

doi:10.1016/j.rpsmen.2018.10.001

Cited by 30 publications

(29 citation statements)

References 52 publications

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“…Application of a predictive model in first psychotic episodes’ (PEPs study), a multicenter, longitudinal, naturalistic follow-up study [ 18 ]. A total of 16 centers throughout Spain participated in this study; fourteen of them were members of the Biomedical Research Networking Center for Mental Health (CIBERSAM) [ 19 ] and two were collaborator centers [ 18 ]. The study was conducted in accordance with the ethical principles of the Declaration of Helsinki.…”

Section: Methodsmentioning

confidence: 99%

Exploring Risk and Resilient Profiles for Functional Impairment and Baseline Predictors in a 2-Year Follow-Up First-Episode Psychosis Cohort Using Latent Class Growth Analysis

Salagre

Grande

Solé

et al. 2020

JCM

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Being able to predict functional outcomes after First-Episode Psychosis (FEP) is a major goal in psychiatry. Thus, we aimed to identify trajectories of psychosocial functioning in a FEP cohort followed-up for 2 years in order to find premorbid/baseline predictors for each trajectory. Additionally, we explored diagnosis distribution within the different trajectories. A total of 261 adults with FEP were included. Latent class growth analysis identified four distinct trajectories: Mild impairment-Improving trajectory (Mi-I) (38.31% of the sample), Moderate impairment-Stable trajectory (Mo-S) (18.39%), Severe impairment-Improving trajectory (Se-I) (12.26%), and Severe impairment-Stable trajectory (Se-S) (31.03%). Participants in the Mi-I trajectory were more likely to have higher parental socioeconomic status, less severe baseline depressive and negative symptoms, and better premorbid adjustment than individuals in the Se-S trajectory. Participants in the Se-I trajectory were more likely to have better baseline verbal learning and memory and better premorbid adjustment than those in the Se-S trajectory. Lower baseline positive symptoms predicted a Mo-S trajectory vs. Se-S trajectory. Diagnoses of Bipolar disorder and Other psychoses were more prevalent among individuals falling into Mi-I trajectory. Our findings suggest four distinct trajectories of psychosocial functioning after FEP. We also identified social, clinical, and cognitive factors associated with more resilient trajectories, thus providing insights for early interventions targeting psychosocial functioning.

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Section: Methodsmentioning

confidence: 99%

Exploring Risk and Resilient Profiles for Functional Impairment and Baseline Predictors in a 2-Year Follow-Up First-Episode Psychosis Cohort Using Latent Class Growth Analysis

Salagre

Grande

Solé

et al. 2020

JCM

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“…The sample consisted of 252 individuals out of whom 202 were euthymic DSM‐IV‐TR BD out‐patients and 50 were HC. Patients were recruited from mental health services in Oviedo and the Bipolar and Depressive Disorders Unit of the Hospital Clinic of Barcelona , all under the umbrella of the Spanish Research Network on Mental Health (CIBERSAM) . The HC volunteers with no history of psychiatric or neurological illness were recruited via advertisement.…”

Section: Methodsmentioning

confidence: 99%

Social cognition in bipolar disorder: the role of sociodemographic, clinical, and neurocognitive variables in emotional intelligence

Varo

Jiménez

Solé

et al. 2019

Acta Psychiatr Scand

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Objective The main aims of this study were to examine the differences in the Emotional Intelligence (EI), the emotional domain of social cognition (SC), between euthymic patients with bipolar disorder (BD) and healthy controls (HC) and to evaluate the contribution of sociodemographic, clinical, and neuropsychological variables to EI. Methods We recruited 202 patients with BD and 50 HC. EI was evaluated using the Mayer–Salovey–Caruso Emotional Intelligence Test (MSCEIT). The sociodemographic, clinical, and neurocognitive variables that showed a significant association with EI were entered into hierarchical multiple regression analysis. Results BD patients obtained significantly lower scores compared to HC in the Emotional Intelligence Quotient (EIQ) and in the Understanding Emotions branch score. The best fitting model for the variables associated with EI in the patients group was a linear combination of gender, estimated IQ, family history of affective diagnosis, and executive function. The model, including these previous variables, explained up to 27.6% of the observed variance (R2 = 0.276, F = 16.406, P < 0.001). Conclusions The identification of variables associated with deficit in EI, such as male gender, lower estimated IQ, family history of affective diagnosis. and lower executive function performance, may help in selecting treatment targets to improve SC, and especially EI, in patients with BD.

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“…Beyond the infectious disease itself, it is to be hoped that this tragedy will underscore the importance of biomedical research and, like public health, receive the recognition it deserves at the budgetary and social level. The hope is that governments will allocate much more of their budgets to collaborative translational research, as Spain has done with the CIBER consortium, 28 and to health registries. 29,30 In short, virtual conferences and distance learning will be greatly enhanced after the pandemic, and this will spare a lot of travel, although not all.…”

Section: Education and Researchmentioning

confidence: 99%

Psychiatry in the aftermath of COVID-19

Vieta

Pérez

Arango

2020

Revista de Psiquiatría y Salud Mental

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Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre-including this research content-immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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CIBERSAM: Ten years of collaborative translational research in mental disorders

Cited by 30 publications

References 52 publications

Exploring Risk and Resilient Profiles for Functional Impairment and Baseline Predictors in a 2-Year Follow-Up First-Episode Psychosis Cohort Using Latent Class Growth Analysis

Exploring Risk and Resilient Profiles for Functional Impairment and Baseline Predictors in a 2-Year Follow-Up First-Episode Psychosis Cohort Using Latent Class Growth Analysis

Social cognition in bipolar disorder: the role of sociodemographic, clinical, and neurocognitive variables in emotional intelligence

Psychiatry in the aftermath of COVID-19

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