Cigarette smoking, but not the presence of H. pylori, is associated with anastomotic ulcers in Roux-en-Y gastric bypass patients

Marginal ulceration after laparoscopic gastric bypass: an analysis of predisposing factors in 260 patients

“…Only 11% of our patients in whom marginal ulcers developed reported NSAID use. Smoking also may predispose patients to the development of marginal ulceration [3,34]. Only one of our patients with marginal ulceration admitted to smoking.…”

“…Furthermore, none of the patients who experienced marginal ulceration and were tested for H. pylori postoperatively had evidence of ongoing infection. Other investigators also have reported this lack of correlation between postoperative H. pylori infection and marginal ulceration [22,34].…”

Perforated marginal ulcers after laparoscopic gastric bypass

“…Other investigators, however, have not seen the positive correlation between H. pylori and marginal ulcers [17]. The exact role the bacteria play in the development of an uncomplicated marginal ulcer is therefore still to be determined.…”

“…Only 11% of the patients who had a marginal ulcer in the series of U. C. Davis [10] reported NSAID use. In two studies, smoking has been linked to marginal ulcers [16,17], but again, it was not significant in the more recent study by Rasmussen et al [10]. The difference may be in the quality of the answers given by the patients.…”

“…Exogenous substances including alcohol, tobacco, and NSAIDs all have been shown to cause gastric ulcers, but their influence on marginal ulcers after bypass has been questioned [16,17]. Only 11% of the patients who had a marginal ulcer in the series of U. C. Davis [10] reported NSAID use.…”