2021
DOI: 10.5606/tgkdc.dergisi.2021.22212
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Cilostazol induces angiogenesis and regulates oxidative stress in a dose-dependent manner: A chorioallantoic membrane study

Abstract: Background: In this study, we aimed to investigate the effects of cilostazol on angiogenesis and oxidative stress using the chorioallantoic membrane model. Methods: In this experimental study, the Ross 308 chick embryos were used. The negative control group (n=10) received no intervention. The positive control group (n=10) consisted of eggs treated with epidermal growth factor for inducing angiogenesis. Three cilostazol groups were designed with 10-7 (n=10), 10-6 (n=10), and 10-5 (n=10) M concentrations. Each… Show more

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Cited by 3 publications
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“…Nowadays, researchers have gained importance to show the role of free radicals in human diseases. The harmful effects of free radicals have been shown to play a role in the formation mechanisms of diseases such as cancer, heart diseases, diabetes mellitus, and many vascular pathologies (21)(22)(23)(24)(25)(26)(27).…”
Section: Discussionmentioning
confidence: 99%
“…Nowadays, researchers have gained importance to show the role of free radicals in human diseases. The harmful effects of free radicals have been shown to play a role in the formation mechanisms of diseases such as cancer, heart diseases, diabetes mellitus, and many vascular pathologies (21)(22)(23)(24)(25)(26)(27).…”
Section: Discussionmentioning
confidence: 99%