1981
DOI: 10.1093/ajhp/38.6.879
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Cimetidine hydrochloride compatibility. II: room temperature stability in intravenous infusion fluids

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“…It is clear, therefore, that early estimates (56) of maximum permissible electrolyte load in a mixed TI" emulsion system have proved to be, in mosr instances, too conservative. It is now appreciated that stability depends on other factors including amino acid profile, amino acid concentration, p H , relative strengths of cations and anions, glucose concentration and the surface characteristics of the container (64,68). T h e maximum p H for emulsion stability is ca 5.0, although even below p H 5 .…”
mentioning
confidence: 99%
“…It is clear, therefore, that early estimates (56) of maximum permissible electrolyte load in a mixed TI" emulsion system have proved to be, in mosr instances, too conservative. It is now appreciated that stability depends on other factors including amino acid profile, amino acid concentration, p H , relative strengths of cations and anions, glucose concentration and the surface characteristics of the container (64,68). T h e maximum p H for emulsion stability is ca 5.0, although even below p H 5 .…”
mentioning
confidence: 99%