“…3,4 The 24-h cycle of HRV (which is defined as a circadian rhythm) may be an important factor because high sympathetic activity that persists throughout a 24-h period may acceleratereceptor down-regulation 19 and promote a reduction of catecholamine stores in the heart. 20,21 Thus, the patients with reduced circadian rhythmicity of HRV may have impaired autonomic nervous function such as diabetic neuropathy, 12 prior myocardial infarction 13,14 or congestive heart failure. 15,16 Previous studies demonstrated that patients with NSVT also have reduced circadian variation of HRV; 7,10 however, we noted that some patients with NSVT have a preserved circadian rhythm.…”