Circulating phage type of &lt;i&gt; Vibrio cholerae&lt;/i&gt; in Mumbai

ObjectivesCholera is a major gastroenteric disease with reports on fluctuation and resistance. Hence, the objective is to determine the trend in seasonality, resistance pattern, prevalent biotypes, serotypes and phage types between 2004 and 2013 among Vibrio cholerae isolates.DesignA retrospective cross-sectional study.SettingsA single-centre study was carried out at a tertiary care hospital in a metropolitan city (Mumbai) of a developing country (India).MethodsRecords of stool specimen cultures of patients with suspected cholera from January 2004 to December 2013 were analysed. The organisms were identified as per standard protocol. Antimicrobial susceptibility testing was performed as per Clinical Laboratory Standard Institute. Biotyping, serotyping and phage typing were carried out. From the confirmed cases of cholera, demographic and laboratory details were noted. Descriptive analysis was used and the data were presented in the form of percentages.ResultsVibrio cholerae was predominant in males and was isolated from 9.41% (439/4664) of stool specimens. Variability was found in terms of the gross appearance of stool specimens, seasonal trend and antibiotic resistance pattern. The antimicrobial susceptibility showed a waxing and waning pattern for most of the antibiotics (ampicillin, cefuroxime, chloramphenicol, tetracycline) tested, while for a few others the strains were either uniformly sensitive (gentamicin, norfloxacin) or resistant (trimethoprim-sulfamethoxazole, nalidixic acid). All isolates belonged to subgroup O1 and biotype El Tor. The most common serotype was Ogawa. The predominant phage type was T2 (old scheme) and T27 (new scheme).ConclusionsThe predominant biotype, serotype and phage type were El Tor, Ogawa and T27 phage, respectively. The changing trends in antimicrobial resistance pattern over the years necessitate continued epidemiological and microbiological surveillance of the disease.

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“…The new typing scheme showed T27 as the predominant phage type, which is similar to other studies 2021 24 25 32 36…”

Section: Discussionsupporting

confidence: 89%

Phenotypic and antibiogram pattern ofV. choleraeisolates from a tertiary care hospital in Mumbai during 2004–2013: a retrospective cross-sectional study

et al. 2016

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“…Therefore, the most common phage type in this part of Mumbai is T27 (74.7%), followed by T26 (18.1%). In the study by Turbadkar et al .,(4) the majority belonged to phage type 27 (97.5%), which is in accordance with the present study.…”

supporting

confidence: 93%

“…Turbadkar et al . (4) from Mumbai have reported Ogawa serotypes in 2004 and all belonged to phage type 4.…”

mentioning

confidence: 99%

Isolation of Vibrio cholerae El Tor Serotype Inaba in 2006 and the most common phage type of V. cholerae in Mumbai

De¹,

Mathur²

2009

Indian J Community Med

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“…This finding is in contrast with several studies from Mumbai, (7) Bikaner (16) and Ludhiana (17), were all strains were belonged to type T4.…”

Section: Indtroductioncontrasting

confidence: 99%

Circulating and Changing Phage Types of V. Cholerae Isolates at L.G. General

Prajapati¹,

Rajput²,

Vinzuda³

et al. 2017

IJABMS

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Circulating phage type of <i> Vibrio cholerae</i> in Mumbai

Cited by 6 publications

References 6 publications

Phenotypic and antibiogram pattern ofV. choleraeisolates from a tertiary care hospital in Mumbai during 2004–2013: a retrospective cross-sectional study

Phenotypic and antibiogram pattern ofV. choleraeisolates from a tertiary care hospital in Mumbai during 2004–2013: a retrospective cross-sectional study

Isolation of Vibrio cholerae El Tor Serotype Inaba in 2006 and the most common phage type of V. cholerae in Mumbai

Circulating and Changing Phage Types of V. Cholerae Isolates at L.G. General

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