2007
DOI: 10.1111/j.1440-1746.2006.04507.x
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Cirrhotic cardiomyopathy: Indian scenario

Abstract: Asian patients with cirrhosis do have evidence of diastolic dysfunction. Cardiac structural and functional parameters did not correlate with the severity of liver dysfunction. Cardiac dysfunction seemed to be the consequence of cirrhosis itself, rather than of alcohol.

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Cited by 32 publications
(26 citation statements)
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“…Cirrhotic patients of our study had liver dysfunction of early, intermediate & late severity 15 patients (30%) were in Child-Pugh class A, 16 patients (32%) were in Child-Pugh class B, 19 Patients (38%) were in class C. In our study there was no significant correlation between the severity of hepatic dysfunction and cardiac changes, which is consistent with one published report from India 1 . As in our study we included 50 cirrhotic subjects and out of this 42 had cirrhotic cardiomyopathy, so prevalence in our study was 84%.…”
Section: Discussionsupporting
confidence: 82%
“…Cirrhotic patients of our study had liver dysfunction of early, intermediate & late severity 15 patients (30%) were in Child-Pugh class A, 16 patients (32%) were in Child-Pugh class B, 19 Patients (38%) were in class C. In our study there was no significant correlation between the severity of hepatic dysfunction and cardiac changes, which is consistent with one published report from India 1 . As in our study we included 50 cirrhotic subjects and out of this 42 had cirrhotic cardiomyopathy, so prevalence in our study was 84%.…”
Section: Discussionsupporting
confidence: 82%
“…Thus, cardiac changes even in patients with alcoholic cirrhosis can be attributed to cirrhosis itself rather than to alcohol consumption. This is in concordance with another Indian study by Jacob et al (13) Alcohol does not appear to be a contributory factor to the development of cirrhotic cardiomyopathy, as only some of the patients with cardiac dysfunction had alcohol as the aetiology of their cirrhosis.…”
Section: Discussionsupporting
confidence: 81%
“…7 The results in our study were similar to previous studies showing evidence of diastolic dysfunction among cirrhotics. 8,9 EDT was shorter in cirrhotic group as compared to controls. The median E deceleration time (ms) in cirrhotics and controls was 170 (100 -229) and 204 (190 -220) respectively and difference was statistically significant (P<0.01).…”
Section: Discussionmentioning
confidence: 69%
“…This result was in contrast to previous studies where EDT was prolonged in cirrhotics as compared to controls. 8 EDT reflects impedance to LV filling and varies with severity of diastolic dysfunction, the value increases in grade 1 diastolic dysfunction and as severity worsens it tends to pseudonormalise or decreases. 10 E/A ratio and IVRT did not show statistically significant difference among cirrhotics and controls.…”
Section: Discussionmentioning
confidence: 99%