Citric acid production by a novel Aspergillus niger isolate: I. Mutagenesis and cost reduction studies

Lotfy, Walid A.; Ghanem, Khaled M.; El‐Helow, Ehab R.

doi:10.1016/j.biortech.2006.11.007

Cited by 77 publications

(35 citation statements)

References 16 publications

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“…Percentage of both yield of citric acid and utilized sugars during fermentation and volumetric productivity of citric were calculated using the following equations, (Lotfy et a , 2007):-Yield of citric acid (%)= (grams of citric acid produced/ grams of original sugar )×100 Sugar utilization (%)= (grams of original sugar-grams of residual sugar / grams of original sugar ) × 100 Volumetric productivity of citric acid = g citric acid produced per liter per hour.…”

Section: Methods Fermentation Processmentioning

confidence: 99%

Utilization of Some Sugar Industrial by- Products and Fructan Storing Crops for Bioproduction of Citric Acid

2010

Alexandria Science Exchange Journal: An International Quarterly

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Two sugar industrial by-products, cane bagasse SCB and sugar beet molasses SBM along with two fructan storing crops ,chicory roots CR and Jerusalem artichoke tubers JA , alone or after mixing were utilized as a carbon source in fermentation medium to produce citric acid by Aspergillus niger strain GQ890276. It was found that the proximate composition and total sugars content of these agro-materials played a role in terms of citric acid production . Moisture ranged from 6.55 to 23.15%; crude fat from zero to 1.55%; crude protein from 3.27 to 8.53%; crude fiber from zero to 47.46% , ash from3.29 to 8.93% ,nitrogen free extract from 44.83 to 87.06 % and total sugar 8.11 to 87.06% among these materials. The fermentation media either containing mixture of CR +SCB and/or CR as carbon source gave high citric acid yield after 7 days of fermentation comparing with other used carbon sources. The citric acid yield was 59.36 g/L in CR +SCB medium .It was 87.80% when calculation was based on the amount of consumed fermentable sugars. Also this media gave the high biomass ( 22.90 g/L) yield.

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Section: Methods Fermentation Processmentioning

confidence: 99%

Utilization of Some Sugar Industrial by- Products and Fructan Storing Crops for Bioproduction of Citric Acid

2010

Alexandria Science Exchange Journal: An International Quarterly

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“…The other variables were fixed at: moisture content 70%, solid substrate pH of 6 and mixed particle (< 2.0 mm). [18,19]. production from SSF using co-culture on wheat straw at 96 hr.…”

Section: 서 론mentioning

confidence: 99%

Effects of Fermentation Parameters on Cellulolytic Enzyme Production under Solid Substrate Fermentation

Kim¹

2014

Korean Chemical Engineering Research

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− The present study was carried out to optimize fermentation parameters for the production of cellulolytic enzymes through solid substrate fermentation of Trichoderma reesei and Aspergillus niger grown on wheat straw. A sequential optimization based on one-factor-at-a-time method was applied to optimize fermentation parameters including temperature, pH, moisture content and particle size. The results of optimization indicated that 40 o C, pH 7, moisture content 75% and particle size between 0.25~0.5 mm were found to be the optimum condition at 96 hr fermentation. Under the optimal condition, co-culture of T. reesei and A. niger produced cellulase activities of 10.3 IU, endoglucanase activity of 100.3 IU, β-glucosidase activity of 22.9 IU and xylanase activity of 2261.7 IU/g dry material were obtained. Cellulolytic enzyme production with optimization showed about 72.6, 48.8, 55.2 and 51.9% increase compared to those obtained from control experiment, respectively.

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“…The constitution (g/dm 3 ) of the fermentation medium used for citric acid production was as described by Lotfy, Ghanem, & El-Helow, (2007) Surface fermentation was carried out in 250 cm 3 Erlenmeyer flasks. The flask containing the fermentation medium was inoculated with 0.5 cm 3 of the inoculum and then incubated at 30 o C.…”

Section: Culture Medium Inoculum and Fermentationmentioning

confidence: 99%

Modelling and Simulation of Citric Acid Production from Corn Starch Hydrolysate Using Aspergillus Niger

Amenaghawon¹,

Aisien²

2012

ENRR

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The kinetics of citric acid fermentation from corn starch hydrolysate using Aspergillus niger ATCC 9142 was studied in a batch fermenter. A general model for citric acid production was formulated. Four kinetic models, Monod, Haldane, logistic and hyperbolic for describing the growth of the fermenting microorganism were explored. The validity of the models in terms of predicting growth of the fermenting organism was determined by fitting each kinetic model to experimental data collected in the course of this work. Comparison of experimental results to model predicted results showed that only the hyperbolic model was able to accurately replicate the experimental results. This was evident from the high level of correlation between the experimental and model predicted results. The kinetic parameters for cell growth, substrate consumption and product formation µ max , Y x/s , Y p/x , K s and K p as calculated by the hyperbolic model are 0.01320h -1 , 0.711g/g, 13.6708g/g, 0.0006g/dm 3 , and 0.2572 g/dm 3 respectively. The validated model was implemented in an advanced equation oriented modelling software to determine the effect of key process parameters on the production of citric acid.Results of simulating the model show that the production of citric acid is a growth associated process. Optimum pH, initial sugar concentration and temperature of for citric acid production were 5.5, 40w/v and 30 o C respectively.

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Citric acid production by a novel Aspergillus niger isolate: I. Mutagenesis and cost reduction studies

Cited by 77 publications

References 16 publications

Utilization of Some Sugar Industrial by- Products and Fructan Storing Crops for Bioproduction of Citric Acid

Utilization of Some Sugar Industrial by- Products and Fructan Storing Crops for Bioproduction of Citric Acid

Effects of Fermentation Parameters on Cellulolytic Enzyme Production under Solid Substrate Fermentation

Modelling and Simulation of Citric Acid Production from Corn Starch Hydrolysate Using Aspergillus Niger

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