Class-specific determination of fluoroquinolones based on a novel chemiluminescence system with molecularly imprinted polymers

A highly sensitive lateral flow immunoassay for the rapid and on-site detection of enrofloxacin in milk

“…Recently, diverse systems and methods with detection advances compared to conventional have been developed for more rapid, easy, and sensitive detection of ENR. For instance, Li et al ( 18 ) developed a molecularly imprinted polymers-chemiluminescence system for the determination of ENR in milk. Aymard et al ( 19 ) fabricated a novel electrochemical immunosensor for the detection of ENR in meat.…”

A highly sensitive impedimetric sensor based on a MIP biomimetic for the detection of enrofloxacin

“…or involve time-consuming analytical processes. [6][7][8][9][10][11][12][13][14] Real-time monitoring of misused antibiotics is difficult to achieve. Facile, time-saving, cost-effective, and highly reliable techniques for the detection of antibiotics, therefore, are in urgent demand.…”

“…Several antibiotic detection methods described in the literature still require electronic instruments (Raman, chromatography, chemiluminescence…) or involve time-consuming analytical processes. 6–14 Real-time monitoring of misused antibiotics is difficult to achieve. Facile, time-saving, cost-effective, and highly reliable techniques for the detection of antibiotics, therefore, are in urgent demand.…”

Portable Smartphone-Based QDs for the Visual Onsite Monitoring of Fluoroquinolone Antibiotics in Actual Food and Environmental Samples

“…Recently, the overuse of antibiotics has aroused increasing public attention because of its adverse effects on food safety and environmental health. − Among them, fluoroquinolones (FQs) are a class of antibiotics that exhibit excellent bactericidal activity in destroying bacterial DNA gyrase and topoisomerase IV, enabling them to be an essential substance against bacteria for improving the economic interests of the breed and pharmaceutical industry. − However, in contrast to the beneficial effects, the misuse of FQs will cause severe side effects including hepatotoxicity, muscle injury, nervous disorders, and permanent disability in extreme situations . Moreover, the emergence of antibiotic-resistant bacteria makes the existence of FQs in the natural environment extremely dangerous. − Considering its widespread application in medicine and poultry farming, the inevitable FQ residues in surface water, soil, or animal-derived foodstuffs could be a threat to human health . Although official authorities around the world have defined the maximum limits of residual FQs in animal-derived foodstuffs, accurate tracking of FQs remains one of the most worrying challenges in establishing reasonable antibiotic management, ensuring food safety and reducing the FQ hazard .…”

“…To this end, various analytical methods have been deeply investigated for reporting the levels of residual FQs in actual agri-food, medicine, and environmental samples, such as chemiluminescence (CL), Fourier transform infrared (FT-IR) spectroscopy, high-performance liquid chromatography (HPLC), microbiological assay, fluorescence spectroscopy, , electrochemistry, immunoassay, capillary electrophoresis (CE), atomic absorption spectrometry (AAS), and surface-enhanced Raman spectroscopy (SERS) . Although the above technologies have satisfactory selectivity and sensitivity to the FQ response, they also have some unavoidable drawbacks, including requiring bulky apparatus, professional technical personals, a complex fabrication process of the response system, high cost, and long time, due to which they fail to meet the requirements of onsite quantification in practical food-related industries as well as environmental concerns, especially in case of emergencies.…”