Classic Kaposi's sarcoma presenting first with gastrointestinal tract involvement in a HIV-negative Inuit male – A case report and review of the literature

Balachandra, Brinda; Tunitsky, Ellen; Dawood, Shaheenah; Hings, Ingrid; Marcus, Victoria

doi:10.1016/j.prp.2006.03.002

Cited by 32 publications

(41 citation statements)

References 8 publications

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“…As reported by a Greek Author, 82% of patients with classic KS refer a gastric asymptomatic lesion. They recommend therefore the execution of a gastroscopy in every patient with a new diagnose of KS (11)(12).…”

Section: Case Reportmentioning

confidence: 99%

Kaposi’s sarcoma: An unusual penile lesion in a HIV negative patient

Rose

Justich

Mantica

et al. 2017

Arch Ital Urol Androl

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Kaposi's sarcoma (KS) of the penis is a very rare lesion and it is usually observed in HIV-infected patients. We introduce a case of KS of the penis in a 75 years old HIV negative patient with a peripheral T-cell lymphoma. He came to our attention with a painful ulcerated red lesion on the glans that stretched from the urethral meatus to the coronal skin. This lesion was found to be a KS balanopreputial in the classical variant. Penile KS must be included in the differential diagnosis of genital diseases especially when the clinical features of the lesion are aspecific and diagnosis can be made histologically by performing a biopsy.KEY WORDS: Kaposi sarcoma; Penile lesion; HIV negative; HHV-8; T-cell lymphoma. The abdominal CT scan showed no inguinal lymph nodes or other suspected lesions. Due to an extended lesion and to the absence of a clear diagnose it was decided to perform a glansectomy. The histopathology examination described a classical balanopreputial KS. Six months later the patient was negative for local recurrence but a secondary gastrointestinal lesion was detected during a whole body CT scan and a gastric biopsy was performed. The patient is currently under therapy with interferon.

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Section: Case Reportmentioning

confidence: 99%

Kaposi’s sarcoma: An unusual penile lesion in a HIV negative patient

Rose

Justich

Mantica

et al. 2017

Arch Ital Urol Androl

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“…For this reason, authors suggest routine gastrointestinal system screening in patients diagnosed as classic type KS. [14] Endoscopy is the preferred method of screening and our patient's panendoscopic , radiological, and systemic dermatological examination did not reveal any pathologies.…”

Section: Discussionmentioning

confidence: 65%

Scrotal Kaposi's Sarcoma in HIV-negative patient: A case report and review of the literature

Yenice

Varnalı

Şeker

et al. 2018

Turkish Journal of Urology

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Kaposi's Sarcoma (KS) is a malignancy that generally effects the skin, and can be systemic with internal organ involvement. It originates from the vascular endothelium. KS's relationship with human immunodeficiency virus (HIV) infection is well known. Isolated scrotal KS in the urogenital system is quite rare and scrotal KS in an HIV-negative patient is limited to a few cases. In this case report, the biopsy result from the violescent nodular lesions on the scrotum of the HIV-negative 81-year-old patient was found compatible with KS and a pathology was not detected in the systemic screening. With a diagnosis of isolated scrotal KS, the patient underwent surgical excision aimed at the lesions on the scrotum. KS is rare in HIV-negative patients and it is associated with human herpes virus-8 infection.

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“…KS of the gastrointestinal tract is not an uncommon disease in acquired immunodeficiency syndrome and can also occur in immunosuppressed patients [16,17]. As reported in the literature, 40% of patients with confirmed Kaposi's sarcoma will develop GI lesions as well.…”

Section: Discussionmentioning

confidence: 97%

Metastatic Kaposi’s Sarcoma Causing Gastrointestinal Bleeding: Report of an Unusual Case

Huang¹

2017

Austin J Gastroenterol

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Kaposi's sarcoma is a vascular tumor associated with human herpesvirus 8 (HHV8) infections that most commonly involve the skin. Kaposi's sarcoma with the gastrointestinal tract is not rare in acquired immunodeficiency syndrome and can also occur in immunosuppressed patients. These patients may present with vague and variable clinical manifestations. Herein, we report a case of a 70-year-old man with Sjogren's syndrome and cutaneous Kaposi sarcoma who presented with gastrointestinal bleeding. On upper endoscopy, infiltrative, circumferential, reddish polypoid lesion involving the body and antrum of the stomach was seen. Histologic examination revealed spindle cell proliferation, and immunohistochemistry stains for human herpes virus-8 and CD34 were positive, supporting the diagnosis of metastatic Kaposi's sarcoma. Following this, we present an overview of literature on gastrointestinal Kaposi's sarcoma with emphasis on diagnosis and management.

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Classic Kaposi's sarcoma presenting first with gastrointestinal tract involvement in a HIV-negative Inuit male – A case report and review of the literature

Cited by 32 publications

References 8 publications

Kaposi’s sarcoma: An unusual penile lesion in a HIV negative patient

Kaposi’s sarcoma: An unusual penile lesion in a HIV negative patient

Scrotal Kaposi's Sarcoma in HIV-negative patient: A case report and review of the literature

Metastatic Kaposi’s Sarcoma Causing Gastrointestinal Bleeding: Report of an Unusual Case

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